Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
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Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activitiesGRK2 in the heart: a GPCR kinase and beyondPleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinaseThe regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neuronsTempol reduces oxidative stress and restores renal dopamine D1-like receptor- G protein coupling and function in hyperglycemic ratsAgonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.Agonist-selective mechanisms of GPCR desensitizationRKIP structure drives its function: a three-state model for regulation of RKIP.Agonist-induced phosphorylation and desensitization of the P2Y2 nucleotide receptor.G protein coupled receptor kinases as therapeutic targets in cardiovascular disease.Cross-regulation of VPAC2 receptor internalization by m2 receptors via c-Src-mediated phosphorylation of GRK2.The evolving impact of g protein-coupled receptor kinases in cardiac health and diseaseInvolvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.Multifactorial Regulation of G Protein-Coupled Receptor Endocytosis.Overexpression of diacylglycerol kinase η enhances Gαq-coupled G protein-coupled receptor signaling.G protein-coupled receptor kinases in normal and failing myocardium.Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization.Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes.Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells.Engineered hyperphosphorylation of the β2-adrenoceptor prolongs arrestin-3 binding and induces arrestin internalization.Homocysteine effects classical pathway of GPCR down regulation: Galpha(q/11), Galpha(12/13), G(i/o).Higher basal serine phosphorylation of D1A receptors in proximal tubules of old Fischer 344 rats.Cross-regulation of VPAC(2) receptor desensitization by M(3) receptors via PKC-mediated phosphorylation of RKIP and inhibition of GRK2.GRK2 as a therapeutic target for heart failure.Heterologous phosphorylation-induced formation of a stability lock permits regulation of inactive receptors by β-arrestins.Adverse Effects on β-Adrenergic Receptor Coupling: Ischemic Postconditioning Failed to Preserve Long-Term Cardiac Function.Inhibition of ADRBK2 by calmodulinPKC phosphorylates GRK2PKCβII inhibits the ubiquitination of β-arrestin2 in an autophosphorylation-dependent manner.
P2860
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P2860
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
@ast
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
@en
type
label
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
@ast
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
@en
prefLabel
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
@ast
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.
@en
P2093
P50
P356
P1476
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin
@en
P2093
J Brockmann
S Dammeier
P304
P356
10.1074/JBC.M008773200
P407
P577
2000-10-19T00:00:00Z