Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).
about
A novel adaptation of the integrin PSI domain revealed from its crystal structureStructure and allosteric regulation of the X 2 integrin I domainStructure of an integrin with an αI domain, complement receptor type 4An internal ligand-bound, metastable state of a leukocyte integrin, α X β 2Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapiesDiscovery of platyhelminth-specific α/β-integrin families and evidence for their role in reproduction in Schistosoma mansoniExpression profile of tumor endothelial marker 7 and a putative ligand in the rat spinal cord and dorsal root ganglionThe N-terminal region and the mid-region complex of the integrin beta 2 subunit.Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin beta subunits.Modulation of integrin activation by an entropic spring in the {beta}-kneeIdentification of interacting hot spots in the beta3 integrin stalk using comprehensive interface designIntegrin structure: new twists and turns in dynamic cell adhesion.Identification of integrin beta subunit mutations that alter affinity for extracellular matrix ligand.Molecular mechanisms of prothrombotic risk due to genetic variations in platelet genes: Enhanced outside-in signaling through the Pro33 variant of integrin beta3.The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.Redox-relevant aspects of the extracellular matrix and its cellular contacts via integrinsLow affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection.ADP-ribosylation of integrin alpha7 modulates the binding of integrin alpha7beta1 to lamininEvidence that monoclonal antibodies directed against the integrin beta subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension.Solution properties of full-length integrin alpha(IIb)beta3 refined models suggest environment-dependent induction of alternative bent /extended resting states.Integrin CD11c/CD18 α-chain phosphorylation is functionally important.Defining the repeating elements in the cysteine-rich region (CRR) of the CD18 integrin beta 2 subunit.The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy.Integrin-like allosteric properties of the catch bond-forming FimH adhesin of Escherichia coli.Amino acid changes in Drosophila alphaPS2betaPS integrins that affect ligand affinity.The human platelet antigen-1b variant of αIIbβ3 allosterically shifts the dynamic conformational equilibrium of this integrin toward the active state.Ligand- and cation-induced structural alterations of the leukocyte integrin LFA-1.
P2860
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P2860
Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Amino acid residues in the PSI ...... the integrin alpha(X)beta(2).
@ast
Amino acid residues in the PSI ...... the integrin alpha(X)beta(2).
@en
type
label
Amino acid residues in the PSI ...... the integrin alpha(X)beta(2).
@ast
Amino acid residues in the PSI ...... the integrin alpha(X)beta(2).
@en
prefLabel
Amino acid residues in the PSI ...... the integrin alpha(X)beta(2).
@ast
Amino acid residues in the PSI ...... the integrin alpha(X)beta(2).
@en
P2860
P356
P1476
Amino acid residues in the PSI ...... the integrin alpha(X)beta(2).
@en
P2093
P2860
P304
P356
10.1074/JBC.M005868200
P407
P577
2000-11-28T00:00:00Z