Sequence requirements for the N-methyl-D-aspartate receptor antagonist activity of conantokin-R.
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From molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypesTransforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxinsCharacterization of conantokin Rl-A: molecular phylogeny as structure/function study.Conantokins inhibit NMDAR-dependent calcium influx in developing rat hippocampal neurons in primary culture with resulting effects on CREB phosphorylation.Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors.Conantokin-Br from Conus brettinghami and selectivity determinants for the NR2D subunit of the NMDA receptor.Classifying neuronal subclasses of the cerebellum through constellation pharmacology.NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins.Subtype-selective antagonism of N-methyl-D-aspartate receptor ion channels by synthetic conantokin peptides.The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors.Specific determinants of conantokins that dictate their selectivity for the NR2B subunit of N-methyl-D-aspartate receptors.Direct binding properties of conantokins to native N-methyl-d-aspartate receptors.
P2860
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P2860
Sequence requirements for the N-methyl-D-aspartate receptor antagonist activity of conantokin-R.
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name
Sequence requirements for the ...... nist activity of conantokin-R.
@ast
Sequence requirements for the ...... nist activity of conantokin-R.
@en
type
label
Sequence requirements for the ...... nist activity of conantokin-R.
@ast
Sequence requirements for the ...... nist activity of conantokin-R.
@en
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Sequence requirements for the ...... nist activity of conantokin-R.
@ast
Sequence requirements for the ...... nist activity of conantokin-R.
@en
P2093
P2860
P356
P1476
Sequence requirements for the ...... nist activity of conantokin-R.
@en
P2093
P2860
P304
P356
10.1074/JBC.M006648200
P407
P577
2000-11-28T00:00:00Z