The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets.

The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets.

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http://www.wikidata.org/entity/Q31635792
RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic isletsInsulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteomeThe mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseasesGoals of treatment for type 2 diabetes: beta-cell preservation for glycemic controlThe Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling.Identifying Novel Candidate Genes Related to Apoptosis from a Protein-Protein Interaction Network.Effect of genetic polymorphisms on the development of secondary failure to sulfonylurea in egyptian patients with type 2 diabetes.Lack of association between the insulin receptor substrates-1 Gly972Arg polymorphism and type-2 diabetes mellitus among Saudis from Eastern Saudi ArabiaRole of nucleolar protein NOM1 in pancreatic islet β cell apoptosis in diabetes.GATA factors promote ER integrity and β-cell survival and contribute to type 1 diabetes risk.From genotype to human β cell phenotype and beyond.Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion.Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation.Kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via Akt-glycogen synthase kinase-3 and Akt-Bad.14-3-3 signaling pathways.Endothelial Dysfunction in Type 2 Diabetes Mellitus.
P2860

The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets.

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http://www.wikidata.org/entity/Q31635792
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2000 nî lūn-bûn
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The common Arg972 polymorphism ...... is of human pancreatic islets.
@ast
The common Arg972 polymorphism ...... is of human pancreatic islets.
@en
type
label
The common Arg972 polymorphism ...... is of human pancreatic islets.
@ast
The common Arg972 polymorphism ...... is of human pancreatic islets.
@en
prefLabel
The common Arg972 polymorphism ...... is of human pancreatic islets.
@ast
The common Arg972 polymorphism ...... is of human pancreatic islets.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P356
P1433
P1476
The common Arg972 polymorphism ...... is of human pancreatic islets.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921