Nucleotide-dependent single- to double-headed binding of kinesin.
about
Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contractionPolarized fluorescence microscopy of individual and many kinesin motors bound to axonemal microtubules.The forward and backward stepping processes of kinesin are gated by ATP bindingModulation of kinesin binding by the C-termini of tubulin.FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry.Simultaneous, coincident optical trapping and single-molecule fluorescenceIdentification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin.Two distinct modes of processive kinesin movement in mixtures of ATP and AMP-PNP.Direct measurements of kinesin torsional properties reveal flexible domains and occasional stalk reversals during stepping.Measuring collective transport by defined numbers of processive and nonprocessive kinesin motorsSensing surface mechanical deformation using active probes driven by motor proteins.Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast.Resource Letter: LBOT-1: Laser-based optical tweezersHow the Load and the Nucleotide State Affect the Actin Filament Binding Mode of the Molecular Motor Myosin V.Kinesin-microtubule binding depends on both nucleotide state and loading direction.Equilibrium and transition between single- and double-headed binding of kinesin as revealed by single-molecule mechanics.Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strainOn the hand-over-hand mechanism of kinesinKinesin walks the line: single motors observed by atomic force microscopy.A universal pathway for kinesin stepping.Coordination between motor domains in processive kinesins.Kinesin motor mechanics: binding, stepping, tracking, gating, and limping.Quasiperiodic distribution of rigor cross-bridges along a reconstituted thin filament in a skeletal myofibril.Walking motion of an overdamped active particle in a ratchet potential.Kinesin-1 structural organization and conformational changes revealed by FRET stoichiometry in live cells.Load-dependent ADP binding to myosins V and VI: implications for subunit coordination and function.Energetics of kinesin-1 stepping mechanism.Insights into the mechanisms of myosin and kinesin molecular motors from the single-molecule unbinding force measurements.Walking molecules.Role of kinesin-1 in the pathogenesis of SPG10, a rare form of hereditary spastic paraplegia.Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules.Key residues on microtubule responsible for activation of kinesin ATPase.Processivity of kinesin motility is enhanced on increasing temperature.Intramolecular strain coordinates kinesin stepping behavior along microtubules.Single-molecule observations of neck linker conformational changes in the kinesin motor protein.Design principles governing chemomechanical coupling of kinesin.Kinesin's front head is gated by the backward orientation of its neck linker.Stepping and stretching. How kinesin uses internal strain to walk processively.Multimotor transport in a system of active and inactive kinesin-1 motors.Computer simulations reveal motor properties generating stable antiparallel microtubule interactions.
P2860
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P2860
Nucleotide-dependent single- to double-headed binding of kinesin.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Nucleotide-dependent single- to double-headed binding of kinesin.
@ast
Nucleotide-dependent single- to double-headed binding of kinesin.
@en
type
label
Nucleotide-dependent single- to double-headed binding of kinesin.
@ast
Nucleotide-dependent single- to double-headed binding of kinesin.
@en
prefLabel
Nucleotide-dependent single- to double-headed binding of kinesin.
@ast
Nucleotide-dependent single- to double-headed binding of kinesin.
@en
P1433
P1476
Nucleotide-dependent single- to double-headed binding of kinesin.
@en
P2093
K Kawaguchi
S Ishiwata
P304
P356
10.1126/SCIENCE.291.5504.667
P407
P577
2001-01-01T00:00:00Z