Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors.
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Slow phases of GABA(A) receptor desensitization: structural determinants and possible relevance for synaptic functionNeuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors.Progesterone withdrawal reduces paired-pulse inhibition in rat hippocampus: dependence on GABA(A) receptor alpha4 subunit upregulation.Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currentsDown-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticityGABAA receptor trafficking-mediated plasticity of inhibitory synapses.Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel.Residues in the first transmembrane domain of the Caenorhabditis elegans GABA(A) receptor confer sensitivity to the neurosteroid pregnenolone sulfate.Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptorEtomidate uniquely modulates the desensitization of recombinant α1β3δ GABA(A) receptors.Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population.Effect of the alpha subunit subtype on the macroscopic kinetic properties of recombinant GABA(A) receptors.The location of a closed channel gate in the GABAA receptor channel.Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus.Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons.Living or dying in three quarter time: neonatal orchestration of hippocampal cell death pathways by androgens and excitatory GABA.Tandem subunits effectively constrain GABAA receptor stoichiometry and recapitulate receptor kinetics but are insensitive to GABAA receptor-associated protein.Homeostatic competition between phasic and tonic inhibitionNeurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome.Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors.Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells.Neurosteroid administration and withdrawal alter GABAA receptor kinetics in CA1 hippocampus of female rats.GABA A Receptor Coupling Junction and Pore GABRB3 Mutations are Linked to Early-Onset Epileptic Encephalopathy.Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics.De novo GABRG2 mutations associated with epileptic encephalopathies.Allosteric Modulation of αβδ GABAA Receptors.Balancing tonic and phasic inhibition in hypothalamic corticotropin releasing hormone neurons.Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation.
P2860
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P2860
Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structural determinants of fas ...... n coupling in GABAa receptors.
@ast
Structural determinants of fas ...... n coupling in GABAa receptors.
@en
type
label
Structural determinants of fas ...... n coupling in GABAa receptors.
@ast
Structural determinants of fas ...... n coupling in GABAa receptors.
@en
prefLabel
Structural determinants of fas ...... n coupling in GABAa receptors.
@ast
Structural determinants of fas ...... n coupling in GABAa receptors.
@en
P2093
P1476
Structural determinants of fas ...... on coupling in GABAa receptors
@en
P2093
M T Bianchi
R L Macdonald
P304
P356
10.1523/JNEUROSCI.21-04-01127.2001
P407
P577
2001-02-01T00:00:00Z