A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues. - Wikidata - wikimedia - TriplyDB

A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues.

A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues.

http://www.wikidata.org/entity/Q31917184

about

Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion CLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.Design and synthesis of new piperidone grafted acetylcholinesterase inhibitors.r-2,c-6-Bis(4-chloro-phen-yl)-c-3,t-3-dimethyl-piperidin-4-one 1-Benzoyl-c-3,t-3-dimethyl-r-2,c-6-diphenyl-piperidin-4-one.13-Hydr-oxy-4,16-dimethyl-4,16-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-7(12),8,10-triene-6,18-dione.19-[(E)-4-Chloro-benzyl-idene]-16-(4-chloro-phen-yl)-2-hydr-oxy-1,11-diaza-hexa-cyclo-[15.3.1.0.0.0.0]henicosa-3(8),4,6-triene-9,18-dione 16-[(E)-Benzyl-idene]-13-hy-droxy-4-methyl-2-phenyl-4,14-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-7(12),8,10-triene-6,17-dione.5-[(E)-2-Bromo-benzyl-idene]-8-(2-bromo-phen-yl)-2-hy-droxy-10-methyl-3,10-di-aza-hexa-cyclo-[10.7.1.1.0.0.0]henicosa-1(20),12,14,16,18-pentaen-6-one.(3E,5E)-1-Acryloyl-3,5-bis-(2-chloro-benzyl-idene)piperidin-4-one.3,5-Bis(4-chloro-benzyl-idene)-1-methyl-piperidin-4-one.Eliminating the heart from the curcumin molecule: monocarbonyl curcumin mimics (MACs).(3E,5E)-3,5-Dibenzyl-idene-1-[3-(piperidin-1-yl)propano-yl]piperidin-4-one.(3E,5E)-1-Acryloyl-3,5-bis-(2,4-dichloro-benzyl-idene)piperidin-4-one hemihydrate 1-Benzyl-3,5-bis-(4-chloro-benzyl-idene)piperidin-4-one.3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: a lead tumor-specific cytotoxin which induces apoptosis and autophagy N-Aroyl-3,5-bis(benzylidene)-4-piperidones: a novel class of antimycobacterial agents.Bis[3,5-bis(benzylidene)-4-oxo-1-piperidinyl]amides: a novel class of potent cytotoxins 3,5-Bis(benzylidene)-4-oxo-1-phosphonopiperidines and related diethyl esters: Potent cytotoxins with multi-drug-resistance reverting properties.3,5-Bis(benzylidene)-1-[3-(2-hydroxyethylthio)propanoyl]piperidin-4-ones: a novel cluster of potent tumor-selective cytotoxins.(3E,5E)-3,5-Bis(4-methyl-benzyl-idene)-1-[3-(piperidin-1-yl)propano-yl]piperidin-4-one Crystal structure of (4-hy-droxy-piperidin-1-yl)(4-methyl-phen-yl)methanone.5-(4-Fluoro-benzyl-idene)-4'-(4-fluoro-phen-yl)-1,1'-dimethyl-dispiro-[piperidine-3,3'-pyrrolidine-2',3''-indoline]-4,2''-dione The synthesis of highly functionalised pyridines using Ghosez-type reactions of dihydropyrazoles 1',1''-Dimethyl-4'-(4-methyl-phen-yl)di-spiro-[11H-indeno-[1,2-b]quinoxaline-11,2'-pyrrolidine-3',3''-piperidin]-4''-one.Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism.1,5-diaryl-3-oxo-1,4-pentadienes: a case for antineoplastics with multiple targets.Crystal structures of three 3-chloro-3-methyl-2,6-di-aryl-piperidin-4-ones.Facile, regio- and diastereoselective synthesis of spiro-pyrrolidine and pyrrolizine derivatives and evaluation of their antiproliferative activities.Synthesis and anticancer evaluation of furfurylidene 4-piperidone analogs.Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes.Syntheses and cytotoxic properties of the curcumin analogs 2,6-bis(benzylidene)-4-phenylcyclohexanones.3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors.Cytotoxic 3,5-bis(benzylidene)piperidin-4-ones and N-acyl analogs displaying selective toxicity for malignant cells.N-acyl-3,5-bis(arylidene)-4-piperidones and related compounds which stimulate fyn kinase.3,5-bis(phenylmethylene)-1-(N-arylmaleamoyl)-4-piperidones: a novel group of cytotoxic agents.Cytotoxic mannich bases of 1-arylidene-2-tetralones.Comparative QSAR Analysis of 3,5-bis (Arylidene)-4-Piperidone Derivatives: the Development of Predictive Cytotoxicity Models.1-Chloro-acetyl-2,6-bis-(2-chloro-phen-yl)-3,5-dimethyl-piperidin-4-one oxime

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A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues.

http://www.wikidata.org/entity/Q31917184

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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A conformational and structure ...... related N-acryloyl analogues.

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A conformational and structure ...... related N-acryloyl analogues.

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A conformational and structure ...... related N-acryloyl analogues.

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A conformational and structure ...... related N-acryloyl analogues.

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A conformational and structure ...... related N-acryloyl analogues.

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Allen TM

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Balzarini J

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De Clercq E

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Kraatz HB

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