Isolation of human O6-alkylguanine-DNA alkyltransferase mutants highly resistant to inactivation by O6-benzylguanine.
about
Erythroid-specific human factor IX delivery from in vivo selected hematopoietic stem cells following nonmyeloablative conditioning in hemophilia B miceFoamy virus vectors for HIV gene therapyActive and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base bindingEarly Chk1 phosphorylation is driven by temozolomide-induced, DNA double strand break- and mismatch repair-independent DNA damageFluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug ResponseApplied molecular evolution of O6-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cellsPoint mutations at multiple sites including highly conserved amino acids maintain activity, but render O6-alkylguanine-DNA alkyltransferase insensitive to O6-benzylguanine.Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.Alkyltransferase-like proteins: molecular switches between DNA repair pathways.Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo.Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selectionLesion-specific DNA-binding and repair activities of human O⁶-alkylguanine DNA alkyltransferase.Differential inactivation of polymorphic variants of human O6-alkylguanine-DNA alkyltransferase.Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.Alkyltransferase-mediated toxicity of 1,3-butadiene diepoxide.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.Effect of O6-alkylguanine-DNA alkyltransferase on genotoxicity of epihalohydrins.Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase.Conserved residue lysine165 is essential for the ability of O6-alkylguanine-DNA alkyltransferase to react with O6-benzylguanine.Alkylation damage repair protein O6-alkylguanine-DNA alkyltransferase from the hyperthermophiles Aquifex aeolicus and Archaeoglobus fulgidus.Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.
P2860
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P2860
Isolation of human O6-alkylguanine-DNA alkyltransferase mutants highly resistant to inactivation by O6-benzylguanine.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Isolation of human O6-alkylgua ...... ctivation by O6-benzylguanine.
@ast
Isolation of human O6-alkylgua ...... ctivation by O6-benzylguanine.
@en
type
label
Isolation of human O6-alkylgua ...... ctivation by O6-benzylguanine.
@ast
Isolation of human O6-alkylgua ...... ctivation by O6-benzylguanine.
@en
prefLabel
Isolation of human O6-alkylgua ...... ctivation by O6-benzylguanine.
@ast
Isolation of human O6-alkylgua ...... ctivation by O6-benzylguanine.
@en
P2093
P1433
P1476
Isolation of human O6-alkylgua ...... ctivation by O6-benzylguanine.
@en
P2093
M Xu-Welliver
S Kanugula
P304
P407
P577
1998-05-01T00:00:00Z