Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
about
Alzheimer's therapeutics: translation of preclinical science to clinical drug developmentTranslational research in nicotine dependenceα7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimumThe α7 nicotinic acetylcholine receptor function in hippocampal neurons is regulated by the lipid composition of the plasma membraneAcquisition and long-term retention of spatial learning in the human immunodeficiency virus-1 transgenic rat: effects of repeated nicotine treatment.The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model.A mutation in the extracellular domain of the α7 nAChR reduces calcium permeability.Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Activation of functional α7-containing nAChRs in hippocampal CA1 pyramidal neurons by physiological levels of choline in the presence of PNU-120596A type-II positive allosteric modulator of α7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats.Comparative pharmacology of rat and human alpha7 nAChR conducted with net charge analysis.Nicotine attenuates beta-amyloid peptide-induced neurotoxicity, free radical and calcium accumulation in hippocampal neuronal cultures.Cholinergic receptors: functional role of nicotinic ACh receptors in brain circuits and disease.Donepezil: an update.Neuronal nicotinic receptors as novel targets for inflammation and neuroprotection: mechanistic considerations and clinical relevance.The effect of alcohol and nicotine abuse on gene expression in the brain.The potential of neuronal nicotinic acetylcholine receptor agonists for treating CNS conditions.Alpha7 nicotinic receptors as therapeutic targets for Parkinson's disease.Dysfunctional Sensory Modalities, Locus Coeruleus, and Basal Forebrain: Early Determinants that Promote Neuropathogenesis of Cognitive and Memory Decline and Alzheimer's Disease.Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca(2+) release from the endoplasmic reticulum.Membrane permeability-guided identification of neuroprotective components from Polygonum cuspidatun.Effects of cholinesterase inhibitors on rat nicotinic receptor levels in vivo and in vitroEvidence of alpha 7 nicotinic acetylcholine receptor expression in retinal pigment epithelial cells.Glial Asthenia and Functional Paralysis: A New Perspective on Neurodegeneration and Alzheimer's Disease.Nicotine enhances the depressive actions of A beta 1-40 on long-term potentiation in the rat hippocampal CA1 region in vivo.The atypical antipsychotic risperidone reverses the recognition memory deficits induced by post-weaning social isolation in rats.
P2860
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P2860
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
@ast
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
@en
type
label
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
@ast
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
@en
prefLabel
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
@ast
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
@en
P1476
Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity.
@en
P2093
P304
P356
10.1016/S0006-3223(00)01100-8
P407
P577
2001-02-01T00:00:00Z