Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release.
about
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteinsCeramide forms channels in mitochondrial outer membranes at physiologically relevant concentrationsRoles of bioactive sphingolipids in cancer biology and therapeuticsTemporal relationships between ceramide production, caspase activation and mitochondrial dysfunction in cell lines with varying sensitivity to anti-Fas-induced apoptosisCeramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik.Enlargement and contracture of C2-ceramide channels.Drug-resistance in human melanoma.Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model.Cellular FLICE-inhibitory protein: an attractive therapeutic target?Mitochondrial ceramide and the induction of apoptosisAdenovirus-mediated expression of mutated forkhead human transcription like-1 suppresses tumor growth in a mouse melanoma xenograft modelInduction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.Sphingosine forms channels in membranes that differ greatly from those formed by ceramide.Erdr1 Suppresses Murine Melanoma Growth via Regulation of Apoptosis.Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITIONInsights into melanoma: targeting the mTOR pathway for therapeutics.Biogenesis and Functions of Exosomes and Extracellular Vesicles.Silencing RhoA inhibits migration and invasion through Wnt/β-catenin pathway and growth through cell cycle regulation in human tongue cancer.Altered mRNA expression related to the apoptotic effect of three xanthones on human melanoma SK-MEL-28 cell line.A caspase-8-independent component in TRAIL/Apo-2L-induced cell death in human rhabdomyosarcoma cells.Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.Expression and function of bcl-2 proteins in melanomaThe bisphosphonate pamidronate induces apoptosis in human melanoma cells in vitro.Conditional expression of exogenous Bcl-X(S) triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts.Studying Mechanisms of Eryptosis.
P2860
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P2860
Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release.
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Resistance to CD95/Fas-induced ...... hondrial cytochrome c release.
@ast
Resistance to CD95/Fas-induced ...... hondrial cytochrome c release.
@en
type
label
Resistance to CD95/Fas-induced ...... hondrial cytochrome c release.
@ast
Resistance to CD95/Fas-induced ...... hondrial cytochrome c release.
@en
prefLabel
Resistance to CD95/Fas-induced ...... hondrial cytochrome c release.
@ast
Resistance to CD95/Fas-induced ...... hondrial cytochrome c release.
@en
P2093
P2860
P1433
P1476
Resistance to CD95/Fas-induced ...... hondrial cytochrome c release.
@en
P2093
Orfanos CE
P2860
P356
10.1016/S0014-5793(00)01491-5
P407
P577
2000-05-01T00:00:00Z