Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells. - Wikidata - wikimedia - TriplyDB

Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells.

Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells.

http://www.wikidata.org/entity/Q33183622

about

PKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners GSK-3: tricks of the trade for a multi-tasking kinase GSK-3 as potential target for therapeutic intervention in cancer Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways The β-catenin destruction complex Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation GSK-3: Functional Insights from Cell Biology and Animal Models.CCL2 disrupts the adherens junction: implications for neuroinflammation Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling A noncatalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activity Functional studies of shaggy/glycogen synthase kinase 3 phosphorylation sites in Drosophila melanogaster.FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A.mTORC1 dependent regulation of REDD1 protein stability.Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons.A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation.Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo.GSK-3 promotes cell survival, growth, and PAX3 levels in human melanoma cells TNF-induced activation of pulmonary microvessel endothelial cells: a role for GSK3beta.Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.Characterization of Wnt/β-catenin signaling in rhabdomyosarcoma.Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines.Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.Signalling activity of beta-catenin targeted to different subcellular compartments.Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium.Tumor necrosis factor-α induces increased lung vascular permeability: a role for GSK3α/β Regulation of β-catenin nuclear dynamics by GSK-3β involves a LEF-1 positive feedback loop.Inhibition of GSK3α/β promotes increased pulmonary endothelial permeability to albumin by reactive oxygen/nitrogen species.MicroRNA-21 promotes tumour malignancy via increased nuclear translocation of β-catenin and predicts poor outcome in APC-mutated but not in APC-wild-type colorectal cancer.ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathway.Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.Augmentation of therapeutic angiogenesis using genetically modified human endothelial progenitor cells with altered glycogen synthase kinase-3beta activity.Identification and analysis of glycogen synthase kinase 3 beta1 interactome.

P2860

Q24310830-64B2CEEC-4D10-403C-9DB1-F23409D7FF15 Q24624069-73DC14D1-1857-421D-8F3E-F94105A3E920 Q27013811-ABA64826-6045-4295-885F-1320F8BCD9D6 Q28177635-960A3FB9-6197-422C-9CBE-F37E9FB31E66 Q28279593-1AD0D325-1CED-44E3-A4BE-A53AFD519C59 Q28302174-BC9A1206-5871-4CF2-B641-B696A46D9EBF Q28566335-4251CEE1-499D-46E1-B4BC-57E23F151869 Q29618700-6A48F0FD-7816-4EFC-B4EA-70D1620BD2F3 Q30472813-1C8B1287-177F-4FB5-AEF9-F5AC7B146BF5 Q30523821-40E4AFED-C93B-4342-8CDC-6CFA7410E819 Q33619569-46EE45EB-78A9-4F17-B7ED-80F067B95ED4 Q33706973-6604ECDC-A93A-46B2-94AC-F10010BB78C2 Q34180579-F6979958-E27E-4A12-98FD-D4619C22738A Q34566865-A3E4A6EE-461D-4F7B-BB4F-17E0EBDD0463 Q34744964-1B50DCC6-9521-4DBA-9104-851D7E307E3D Q35071377-ADCFCEE2-6872-4147-A2DD-8F9C2DC61B89 Q35575758-B2883235-54AA-4D30-86F5-7948B961817F Q35755034-F8792B7B-EBBB-40BC-994B-E75EE273114A Q35804128-C7283278-7648-4EAB-962F-D6515B5FB065 Q36089376-565AC424-2919-4911-A29A-1433DE6CB82B Q36173889-71AE78E1-34A5-43EA-B4FC-4BC3AF006326 Q37162769-00D77E78-8FFB-4152-808E-E4741902AF9B Q38807957-BEA99592-E7C8-4C4D-A336-6FF0DDDBBCC8 Q39101031-3AEC8CDD-D909-4336-8BBE-E771A3CBD5AB Q40125072-AA14E0CF-7EA7-4AC5-9350-F7F8F959111A Q40260863-92372FBE-0522-4162-8A63-6362B36F924E Q40597673-C5587506-5AEF-47A8-B1DC-E2F10DA1F3F0 Q41849965-D107D108-98E0-4DE7-9B73-4AFB4589AFB5 Q42092190-7924920A-F3E8-4847-B705-9F18905C801F Q42703003-75F56F44-00BC-4F6E-B2CD-61AD79232DA7 Q42811839-4508E24E-D09A-4135-9956-38D522795955 Q42924374-4E137DFB-AFBA-463A-ACAF-664160DC53B5 Q44577216-868C4244-C06F-406D-AF79-C33A24A3CCC8 Q47136896-716CE573-F7C2-4DFA-A9CD-DC56F1D6DA57 Q52551167-E0D536D4-9261-479D-ABE0-A5967DC1841A Q53635273-5287CEB5-17C5-4362-9057-8FD058AB8683 Q54443469-76E3FF75-3658-487E-938E-4DE3E023B4AE

P2860

Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells.

http://www.wikidata.org/entity/Q33183622

description

2002 nî lūn-bûn

@nan

2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Expression and characterizatio ...... osphorylation in intact cells.

@ast

Expression and characterizatio ...... osphorylation in intact cells.

@en

type

label

Expression and characterizatio ...... osphorylation in intact cells.

@ast

Expression and characterizatio ...... osphorylation in intact cells.

@en

prefLabel

Expression and characterizatio ...... osphorylation in intact cells.

@ast

Expression and characterizatio ...... osphorylation in intact cells.

@en

P1433

Q33183622-BA6A9833-24F0-49ED-A0A3-90D9827C79F4

P1476

Q33183622-41AD74B4-5466-4713-ACE8-B93FC2CBC9CB

P2093

Q33183622-0B8028A2-6D52-459E-AE09-2F9D1A3C202F

Q33183622-33BE8EFD-524F-4D27-9B94-89634A6317F5

Q33183622-A46B10D6-7427-4D29-8B32-DD3D016C6A34

Q33183622-AD9359B6-2337-45C2-ACAC-3138C08E8AE9

P2860

Q33183622-0AAB5398-B6CD-4895-AB95-459BE8AF8DC5

Q33183622-0FB75655-47BC-47CD-98A9-3A33C0B90169

Q33183622-1C420876-FBEC-491E-B9CD-4F507B915AF1

Q33183622-200B0C57-1BAF-4AAA-B37A-1492032E1E1E

Q33183622-2144557B-8484-4EC8-9C07-80AB4E837033

Q33183622-2CEDCDBB-9D05-4D2C-AEE4-23E288D4857E

Q33183622-358E2240-7453-45E7-B948-D1A20BA275D8

Q33183622-4467C3C4-6239-4419-B030-654B6DECA8D2

Q33183622-473A7B7A-DF80-4119-8DFF-08D8E79F7EFE

Q33183622-58E7F23D-FCBF-47C0-978A-70839624F544

P304

Q33183622-D962ABE8-F10C-472D-B90B-F60C4C2AC711

P31

Q33183622-250C4264-394A-4C25-879F-610AC0EEEAC9

P356

Q33183622-C63416C1-CBF2-4921-B89E-02FEE668A4C8

P407

Q33183622-186E7EF9-D4AE-46C2-9141-1FE2FA95394D

P433

Q33183622-2232DDDB-760F-4898-91C0-8D84400C128F

P478

Q33183622-92F771C4-6BEE-4394-BD58-9E5E3862DD7B

P577

Q33183622-AF352AA4-DDE8-4FC2-8A5B-F1B64676EE9F

P5875

Q33183622-ECABF544-AAA0-4996-89E4-74856857BB53

P698

Q33183622-223C4F2C-966B-44B0-8853-CAFF0779252E

P921

Q33183622-DA1A56D8-9F66-4AA0-99B0-7E4D88A70056

P356

P1433

Journal of Biological Chemistry

P1476

Expression and characterizatio ...... osphorylation in intact cells.

@en

P2093

Ainsley A Culbert

http://www.w3.org/2001/XMLSchema#string

Alastair D Reith

http://www.w3.org/2001/XMLSchema#string

Elena Di Daniel

http://www.w3.org/2001/XMLSchema#string

Thilo Hagen

http://www.w3.org/2001/XMLSchema#string

P2860

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Signal transduction by the Wnt family of ligands

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

Structure of GSK3beta reveals a primed phosphorylation mechanism

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation

P304

23330-23335

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M201364200

http://www.w3.org/2001/XMLSchema#string

P407

P433

26

http://www.w3.org/2001/XMLSchema#string

P478

277

http://www.w3.org/2001/XMLSchema#string

P577

2002-04-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11401295

http://www.w3.org/2001/XMLSchema#string

P698

11967263

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation