Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
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Glycogen synthase kinase 3: more than a namesakeStructural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6GSK-3: Functional Insights from Cell Biology and Animal Models.Essential roles for GSK-3s and GSK-3-primed substrates in neurotrophin-induced and hippocampal axon growth.GSK-3 in Neurodegenerative Diseases.What Are the bona fide GSK3 Substrates?GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons.Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease.Morphine Reduces Myocardial Infarct Size via Heat Shock Protein 90 in Rodents.Curcumin: a natural substance with potential efficacy in Alzheimer's disease.Natural antisense transcripts are co-expressed with sense mRNAs in synaptoneurosomes of adult mouse forebrainThe nuclear localization of glycogen synthase kinase 3β is required its putative PY-nuclear localization sequences.Therapeutic strategies for tau mediated neurodegeneration.An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum.Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies.Understanding the relationship between GSK-3 and Alzheimer's disease: a focus on how GSK-3 can modulate synaptic plasticity processes.New insights into the role of glycogen synthase kinase-3 in Alzheimer's disease.BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells.Loss of Endothelial Nitric Oxide Synthase Promotes p25 Generation and Tau Phosphorylation in a Murine Model of Alzheimer's Disease.Delta-catenin/NPRAP: A new member of the glycogen synthase kinase-3beta signaling complex that promotes beta-catenin turnover in neuronsInterleukin-1 receptor type 1 is a substrate for gamma-secretase-dependent regulated intramembrane proteolysis.A ubiquitin-binding CUE domain in presenilin-1 enables interaction with K63-linked polyubiquitin chains.Regulation of cell survival mechanisms in Alzheimer's disease by glycogen synthase kinase-3Deconstructing GSK-3: The Fine Regulation of Its Activity.GSK3beta activity modifies the localization and function of presenilin 1.Atlas stumbled: kinesin light chain-1 variant E triggers a vicious cycle of axonal transport disruption and amyloid-β generation in Alzheimer's disease.The Presenilin loop region is essential for Glycogen synthase kinase 3 beta mediated functions on motor proteins during axonal transport.
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Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
@en
type
label
Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
@en
prefLabel
Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
@en
P2860
P1433
P1476
Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
@en
P2093
Ciara Twomey
Justin V McCarthy
P2860
P304
P356
10.1016/J.FEBSLET.2006.06.035
P407
P577
2006-06-22T00:00:00Z