Binol quinone methides as bisalkylating and DNA cross-linking agents.
about
Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.Reactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes.Sterically congested quinone methides in photodehydration reactions of 4-hydroxybiphenyl derivatives and investigation of their antiproliferative activity.Zwitterionic biphenyl quinone methides in photodehydration reactions of 3-hydroxybiphenyl derivatives: laser flash photolysis and antiproliferation study.The excited state antiaromatic benzene ring: a molecular Mr Hyde?Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.Photochemical formation of quinone methides from peptides containing modified tyrosine.ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block.The Generation and Reactions of Quinone Methides.The leaving group strongly affects H₂O₂-induced DNA cross-linking by arylboronates.Selective and Reversible Photochemical Derivatization of Cysteine Residues in Peptides and Proteins.Photo-triggered fluorescent theranostic prodrugs as DNA alkylating agents for mechlorethamine release and spatiotemporal monitoring.Enhancement of antiproliferative activity by phototautomerization of anthrylphenols.Synthesis and biological studies of the thiols-triggered anticancer prodrug for a more effective cancer therapy.Fluoride as an inducible DNA cross-linking agent for new antitumor prodrug.Photochemical Generation of Benzyl Cations That Selectively Cross-Link Guanine and Cytosine in DNA.Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells.Aromatic nitrogen mustard-based prodrugs: activity, selectivity, and the mechanism of DNA cross-linking.Observation of excited state proton transfer reactions in 2-phenylphenol and 2-phenyl-1-naphthol and formation of quinone methide species.G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy.Substituent effects on oxidation-induced formation of quinone methides from arylboronic ester precursors.Dynamic cross-linking is retained in duplex DNA after multiple exchange of strands.Bipyridyl ligands as photoactivatable mono- and bis-alkylating agents capable of DNA cross-linking
P2860
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P2860
Binol quinone methides as bisalkylating and DNA cross-linking agents.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Binol quinone methides as bisalkylating and DNA cross-linking agents.
@ast
Binol quinone methides as bisalkylating and DNA cross-linking agents.
@en
type
label
Binol quinone methides as bisalkylating and DNA cross-linking agents.
@ast
Binol quinone methides as bisalkylating and DNA cross-linking agents.
@en
prefLabel
Binol quinone methides as bisalkylating and DNA cross-linking agents.
@ast
Binol quinone methides as bisalkylating and DNA cross-linking agents.
@en
P2093
P356
P1476
Binol quinone methides as bisalkylating and DNA cross-linking agents.
@en
P2093
Manlio Palumbo
Mauro Freccero
Sara N Richter
Stefano Colloredo Mels
Stefano Maggi
P304
13973-13979
P356
10.1021/JA047655A
P407
P577
2004-11-01T00:00:00Z