Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.
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The domestication of ortho-quinone methidesRedox-neutral α-oxygenation of amines: reaction development and elucidation of the mechanism.Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs.Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.Michael Additions of Highly Basic Enolates to ortho-Quinone Methides.Photochemical formation of quinone methides from peptides containing modified tyrosine.Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase.ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block.A dual Lewis base activation strategy for enantioselective carbene-catalyzed annulations.Few constraints limit the design of quinone methide-oligonucleotide self-adducts for directing DNA alkylation.The Generation and Reactions of Quinone Methides.The leaving group strongly affects H₂O₂-induced DNA cross-linking by arylboronates.Selective and Reversible Photochemical Derivatization of Cysteine Residues in Peptides and Proteins.A review of the electrophilic reaction chemistry involved in covalent DNA binding.Experimental approaches to identify cellular G-quadruplex structures and functions.Self-immolative spacers: kinetic aspects, structure-property relationships, and applications.Oxidation-Responsive Aliphatic Polycarbonates from N-Substituted Eight-Membered Cyclic Carbonate: Synthesis and Degradation Study.Photo-triggered fluorescent theranostic prodrugs as DNA alkylating agents for mechlorethamine release and spatiotemporal monitoring.Enhancement of antiproliferative activity by phototautomerization of anthrylphenols.Applications of ortho-quinone methide intermediates in catalysis and asymmetric synthesis.Fluoride as an inducible DNA cross-linking agent for new antitumor prodrug.Inducible alkylation of DNA by a quinone methide-peptide nucleic acid conjugate.Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells.Light activation for the versatile and accurate kinetic analysis of disassembly of self-immolative spacers.ortho-Quinones and Analogues Thereof: Highly Reactive Intermediates for Fast and Selective Biofunctionalization.Chiral N,N'-Dioxide-Scandium(III) Complex-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of ortho-Hydroxybenzyl Alcohols with C3-Substituted N-Protected Indoles.Chemoselective reduction and self-immolation based FRET probes for detecting hydrogen sulfide in solution and in cells.Photogenerated quinone methides as protein affinity labeling reagents.Substituent effects on oxidation-induced formation of quinone methides from arylboronic ester precursors.Dynamic cross-linking is retained in duplex DNA after multiple exchange of strands.Mannich base-connected syntheses mediated by ortho-quinone methides.Bipyridyl ligands as photoactivatable mono- and bis-alkylating agents capable of DNA cross-linking
P2860
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P2860
Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Substituents on quinone methid ...... of their nucleophilic adducts.
@ast
Substituents on quinone methid ...... of their nucleophilic adducts.
@en
Substituents on quinone methid ...... of their nucleophilic adducts.
@nl
type
label
Substituents on quinone methid ...... of their nucleophilic adducts.
@ast
Substituents on quinone methid ...... of their nucleophilic adducts.
@en
Substituents on quinone methid ...... of their nucleophilic adducts.
@nl
prefLabel
Substituents on quinone methid ...... of their nucleophilic adducts.
@ast
Substituents on quinone methid ...... of their nucleophilic adducts.
@en
Substituents on quinone methid ...... of their nucleophilic adducts.
@nl
P2093
P2860
P356
P1476
Substituents on quinone methid ...... of their nucleophilic adducts
@en
P2093
Charles H Mitchell
Kristen N Frankenfield
Ruggero Dondi
Stefano Colloredo-Melz
Steven E Rokita
P2860
P304
11940-11947
P356
10.1021/JA062948K
P407
P577
2006-09-01T00:00:00Z