Modulation of radiation response by histone deacetylase inhibition.
about
HDAC inhibitor PCI-24781 decreases RAD51 expression and inhibits homologous recombinationHistone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repairSynthetic nanoparticles for delivery of radioisotopes and radiosensitizers in cancer therapyEpigenetic modulators as therapeutic targets in prostate cancerAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerDownregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factorCancer biology: mechanism of antitumour action of vorinostat (suberoylanilide hydroxamic acid), a novel histone deacetylase inhibitorPhase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study.Vorinostat in solid and hematologic malignanciesAdvances in epigenetic glioblastoma therapy.Molecularly targeted therapies for malignant glioma: rationale for combinatorial strategies.Bortezomib-induced sensitization of malignant human glioma cells to vorinostat-induced apoptosis depends on reactive oxygen species production, mitochondrial dysfunction, Noxa upregulation, Mcl-1 cleavage, and DNA damage.Chromatin-regulating proteins as targets for cancer therapy.A high content clonogenic survival drug screen identifies mek inhibitors as potent radiation sensitizers for KRAS mutant non-small-cell lung cancerCombination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell linesHDAC inhibitor, valproic acid, induces p53-dependent radiosensitization of colon cancer cells.Experimental approaches for the treatment of malignant gliomas.Radiosensitization in prostate cancer: mechanisms and targetsEvaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaksVorinostat (NSC# 701852) in patients with relapsed non-small cell lung cancer: a Wisconsin Oncology Network phase II study.Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition.Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo.Nanoparticle formulations of histone deacetylase inhibitors for effective chemoradiotherapy in solid tumors.The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cellsAberrant DNA methylation and prostate cancer.Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms.Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems.Targeting Histone Deacetylases in Diseases: Where Are We?In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model.Epigenetic regulation of prostate cancerDNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activityPostradiation sensitization of the histone deacetylase inhibitor valproic acidVorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts.Molecular targets for tumor radiosensitization.Synergistic inhibition of hepatocellular carcinoma growth by cotargeting chromatin modifying enzymes and poly (ADP-ribose) polymerases.BRCA1-associated complexes: new targets to overcome breast cancer radiation resistance.Motexafin-gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a children's oncology group phase 2 study.Effect of Chromatin Structure on the Extent and Distribution of DNA Double Strand Breaks Produced by Ionizing Radiation; Comparative Study of hESC and Differentiated Cells Lines.Implication of abnormal epigenetic patterns for human diseases.Recurrent glioblastoma multiforme: advances in treatment and promising drug candidates.
P2860
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P2860
Modulation of radiation response by histone deacetylase inhibition.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Modulation of radiation response by histone deacetylase inhibition.
@ast
Modulation of radiation response by histone deacetylase inhibition.
@en
type
label
Modulation of radiation response by histone deacetylase inhibition.
@ast
Modulation of radiation response by histone deacetylase inhibition.
@en
prefLabel
Modulation of radiation response by histone deacetylase inhibition.
@ast
Modulation of radiation response by histone deacetylase inhibition.
@en
P2093
P1476
Modulation of radiation response by histone deacetylase inhibition.
@en
P2093
Eric Armstrong
Geetha Vallabhaneni
Paul M Harari
Prakash Chinnaiyan
Shyh-Min Huang
P304
P356
10.1016/J.IJROBP.2004.12.088
P407
P577
2005-05-01T00:00:00Z