HDAC inhibitor, valproic acid, induces p53-dependent radiosensitization of colon cancer cells.
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Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repairCHK2 is involved in the p53-independent radiosensitizing effects of valproic acid.The Effect of VPA on Increasing Radiosensitivity in Osteosarcoma Cells and Primary-Culture Cells from Chemical Carcinogen-Induced Breast Cancer in Rats.The Effect of Sodium Valproate on the Glioblastoma U87 Cell Line Tumor Development on the Chicken Embryo Chorioallantoic Membrane and on EZH2 and p53 Expression.Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis.Chromatin-regulating proteins as targets for cancer therapy.New perspectives of valproic acid in clinical practice.Grand rounds at the National Institutes of Health: HDAC inhibitors as radiation modifiers, from bench to clinicConnectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapiesValproic acid promotes radiosensitization in meningioma stem-like cells.In Vitro and In Vivo Radiosensitizing Effect of Valproic Acid on Fractionated IrradiationValproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells.The histone deacetylase inhibitor PCI-24781 as a putative radiosensitizer in pediatric glioblastoma cell lines.Low-dose valproic acid enhances radiosensitivity of prostate cancer through acetylated p53-dependent modulation of mitochondrial membrane potential and apoptosis.The synergistic effects of traditional Chinese herbs and radiotherapy for cancer treatmentInfluence of a novel histone deacetylase inhibitor panobinostat (LBH589) on the growth of ovarian cancer.Histone deacetylase inhibitor, valproic acid, radiosensitizes the C6 glioma cell line in vitro.Delphinidin induces apoptosis via cleaved HDAC3-mediated p53 acetylation and oligomerization in prostate cancer cells.Dual Functional Mesoporous Silicon Nanoparticles Enhance the Radiosensitivity of VPA in Glioblastoma.Recently identified and potential targets for colon cancer treatment.Therapeutic strategies to enhance the anticancer efficacy of histone deacetylase inhibitors.Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results.Targeting chromatin to improve radiation response.Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition.Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines.The Histone Deacetylase Inhibitor Valproic Acid Sensitizes Gemcitabine-Induced Cytotoxicity in Gemcitabine-Resistant Pancreatic Cancer Cells Possibly Through Inhibition of the DNA Repair Protein Gamma-H2AX.Chromatin status of apoptosis genes correlates with sensitivity to chemo-, immune- and radiation therapy in colorectal cancer cell lines.Synergistic anticancer activity of valproate combined with nicotinamide enhances anti-proliferation response and apoptosis in MIAPaca2 cells.HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.Histone deacetylase inhibitor potentiates chemotherapy-induced apoptosis through Bim upregulation in Burkitt's lymphoma cells.Sodium valproate inhibits the growth of human cholangiocarcinoma in vitro and in vivo.Effect of valproic acid on the outcome of glioblastoma multiforme.Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53.Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation.Combination of sorafenib and Valproic acid synergistically induces cell apoptosis and inhibits hepatocellular carcinoma growth via down-regulating Notch3 and pAkt.HDAC inhibitors show differential epigenetic regulation and cell survival strategies on p53 mutant colon cancer cells.Valproic acid and its inhibition of tumor growth in systemic malignancies: beyond gliomas.
P2860
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P2860
HDAC inhibitor, valproic acid, induces p53-dependent radiosensitization of colon cancer cells.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@ast
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@en
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@nl
type
label
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@ast
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@en
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@nl
prefLabel
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@ast
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@en
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@nl
P2093
P2860
P356
P1476
HDAC inhibitor, valproic acid, ...... ization of colon cancer cells.
@en
P2093
Eric Radany
Jeffrey Y C Wong
Patty Wong
Xufeng Chen
P2860
P304
P356
10.1089/CBR.2009.0629
P577
2009-12-01T00:00:00Z