Rapid generation of specific antibodies by enhanced homologous recombination.
about
Genetic manipulation of an exogenous non-immunoglobulin protein by gene conversion machinery in a chicken B cell lineB Cell-Based Seamless Engineering of Antibody Fc DomainsAntibody discovery ex vivo accelerated by the LacO/LacI regulatory networkChromatin structure regulates gene conversion.Lentivirus display: stable expression of human antibodies on the surface of human cells and virus particlesGenetic variation stimulated by epigenetic modification.Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes.The BRCT domain of PARP-1 is required for immunoglobulin gene conversion.The transcriptome landscape of early maize meiosisB-cell display-based one-step method to generate chimeric human IgG monoclonal antibodiesCoupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodiesAffinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells.Bloom DNA helicase facilitates homologous recombination between diverged homologous sequencesHarnessing gene conversion in chicken B cells to create a human antibody sequence repertoire.Anti-Semaphorin 3A neutralization monoclonal antibody prevents sepsis development in lipopolysaccharide-treated mice.NEURONAL DEVELOPMENT. Glycerophospholipid regulation of modality-specific sensory axon guidance in the spinal cord.Directed evolution of human scFvs in DT40 cells.Protein evolution by hypermutation and selection in the B cell line DT40MSH6- or PMS2-deficiency causes re-replication in DT40 B cells, but it has little effect on immunoglobulin gene conversion or on repair of AID-generated uracils.Modulation of immunoglobulin gene conversion in chicken DT40 by enhancing histone acetylation, and its application to antibody engineering.Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line.Enlightenment of yeast mitochondrial homoplasmy: diversified roles of gene conversion.Technologies of directed protein evolution in vivo.Genetic diversification by somatic gene conversion.DNA polymerases nu and theta are required for efficient immunoglobulin V gene diversification in chicken.The 9-1-1 DNA clamp is required for immunoglobulin gene conversion.AID Biology: A pathological and clinical perspective.Gene Conversion-Like Events in the Diversification of Human Rearranged IGHV3-23*01 Gene Sequences.Distinct chromatin modulators regulate the formation of accessible and repressive chromatin at the fission yeast recombination hotspot ade6-M26.5th Annual Monoclonal Antibodies Conference: March 24-25, 2009, London, UK.Coupling recombinase-mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells.Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites
P2860
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P2860
Rapid generation of specific antibodies by enhanced homologous recombination.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Rapid generation of specific antibodies by enhanced homologous recombination.
@ast
Rapid generation of specific antibodies by enhanced homologous recombination.
@en
type
label
Rapid generation of specific antibodies by enhanced homologous recombination.
@ast
Rapid generation of specific antibodies by enhanced homologous recombination.
@en
prefLabel
Rapid generation of specific antibodies by enhanced homologous recombination.
@ast
Rapid generation of specific antibodies by enhanced homologous recombination.
@en
P2093
P2860
P356
P1433
P1476
Rapid generation of specific antibodies by enhanced homologous recombination.
@en
P2093
Hidetaka Seo
Hiromu Murofushi
Kunihiro Ohta
Mieko Masuoka
Takehiko Shibata
P2860
P2888
P304
P356
10.1038/NBT1092
P577
2005-05-29T00:00:00Z