Protein evolution by hypermutation and selection in the B cell line DT40
about
RAB-10-Dependent Membrane Transport Is Required for Dendrite ArborizationDirected molecular evolution to design advanced red fluorescent proteinsA cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation.Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells.Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire.Engineering and characterizing monomeric fluorescent proteins for live-cell imaging applications.Targeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences.Usefulness of a Darwinian system in a biotechnological application: evolution of optical window fluorescent protein variants under selective pressure.The unfolded protein response is required for dendrite morphogenesis.Directed evolution of human scFvs in DT40 cells.Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM.Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line.Directed evolution: selection of the host organism.Technologies of directed protein evolution in vivo.A double-strand break can trigger immunoglobulin gene conversionDirected evolution of mammalian anti-apoptosis proteins by somatic hypermutationAID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity.Directed evolution of an angiopoietin-2 ligand trap by somatic hypermutation and cell surface display.Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.Transient AID expression for in situ mutagenesis with improved cellular fitness.
P2860
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P2860
Protein evolution by hypermutation and selection in the B cell line DT40
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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2007年學術文章
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2007年學術文章
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name
Protein evolution by hypermutation and selection in the B cell line DT40
@ast
Protein evolution by hypermutation and selection in the B cell line DT40
@en
type
label
Protein evolution by hypermutation and selection in the B cell line DT40
@ast
Protein evolution by hypermutation and selection in the B cell line DT40
@en
prefLabel
Protein evolution by hypermutation and selection in the B cell line DT40
@ast
Protein evolution by hypermutation and selection in the B cell line DT40
@en
P2093
P2860
P356
P1476
Protein evolution by hypermutation and selection in the B cell line DT40
@en
P2093
Hiroaki Kudo
Hiroshi Arakawa
Jean-Marie Buerstedde
Joachim W Ellwart
Michael A Rieger
Randolph B Caldwell
Vera Batrak
P2860
P356
10.1093/NAR/GKM616
P407
P577
2007-12-11T00:00:00Z