Protein evolution by hypermutation and selection in the B cell line DT40 - Wikidata - wikimedia - TriplyDB

Protein evolution by hypermutation and selection in the B cell line DT40

Protein evolution by hypermutation and selection in the B cell line DT40

http://www.wikidata.org/entity/Q36471434

about

RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization Directed molecular evolution to design advanced red fluorescent proteins A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation.Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells.Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire.Engineering and characterizing monomeric fluorescent proteins for live-cell imaging applications.Targeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences.Usefulness of a Darwinian system in a biotechnological application: evolution of optical window fluorescent protein variants under selective pressure.The unfolded protein response is required for dendrite morphogenesis.Directed evolution of human scFvs in DT40 cells.Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM.Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line.Directed evolution: selection of the host organism.Technologies of directed protein evolution in vivo.A double-strand break can trigger immunoglobulin gene conversion Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity.Directed evolution of an angiopoietin-2 ligand trap by somatic hypermutation and cell surface display.Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.Transient AID expression for in situ mutagenesis with improved cellular fitness.

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Protein evolution by hypermutation and selection in the B cell line DT40

http://www.wikidata.org/entity/Q36471434

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

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2007年學術文章

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name

Protein evolution by hypermutation and selection in the B cell line DT40

@ast

Protein evolution by hypermutation and selection in the B cell line DT40

@en

type

label

Protein evolution by hypermutation and selection in the B cell line DT40

@ast

Protein evolution by hypermutation and selection in the B cell line DT40

@en

prefLabel

Protein evolution by hypermutation and selection in the B cell line DT40

@ast

Protein evolution by hypermutation and selection in the B cell line DT40

@en

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Nucleic Acids Research

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Protein evolution by hypermutation and selection in the B cell line DT40

@en

P2093

Hiroaki Kudo

http://www.w3.org/2001/XMLSchema#string

Hiroshi Arakawa

http://www.w3.org/2001/XMLSchema#string

Jean-Marie Buerstedde

http://www.w3.org/2001/XMLSchema#string

Joachim W Ellwart

http://www.w3.org/2001/XMLSchema#string

Michael A Rieger

http://www.w3.org/2001/XMLSchema#string

Randolph B Caldwell

http://www.w3.org/2001/XMLSchema#string

Vera Batrak

http://www.w3.org/2001/XMLSchema#string

P2860

Efficiently folding and circularly permuted variants of the Sapphire mutant of GFP

Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate

Mutant loxP vectors for selectable marker recycle and conditional knock-outs

Genetic manipulation of an exogenous non-immunoglobulin protein by gene conversion machinery in a chicken B cell line

Crystal structure of venus, a yellow fluorescent protein with improved maturation and reduced environmental sensitivity

Crystal structure of the Aequorea victoria green fluorescent protein

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

FACS-optimized mutants of the green fluorescent protein (GFP)

Rapid generation of specific antibodies by enhanced homologous recombination.

In vitro evolution of proteins.

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e1

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scholarly article

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10.1093/NAR/GKM616

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1

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36

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2007-12-11T00:00:00Z

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5775599

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18073192

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protein evolution

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2248763

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