p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis. - Wikidata - wikimedia - TriplyDB

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

http://www.wikidata.org/entity/Q33226681

about

Stress kinases in the modulation of metabolism and energy balance Energy metabolism in the liver Hepatocyte growth factor family negatively regulates hepatic gluconeogenesis via induction of orphan nuclear receptor small heterodimer partner in primary hepatocytes Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMP-activated kinase The glucagon receptor is required for the adaptive metabolic response to fasting Exposure to excess insulin (glargine) induces type 2 diabetes mellitus in mice fed on a chow diet.Leucine facilitates insulin signaling through a Gαi protein-dependent signaling pathway in hepatocytes.Prolonged exposure to insulin induces mitochondrion-derived oxidative stress through increasing mitochondrial cholesterol content in hepatocytes.p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagy.Insulin and insulin signaling play a critical role in fat induction of insulin resistance in mouse.Fine-tuned regulation of the PGC-1α gene transcription by different intracellular signaling pathways.Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: inhibition of FoxO1-dependent expression of key autophagy genes by insulin.Insulin is a stronger inducer of insulin resistance than hyperglycemia in mice with type 1 diabetes mellitus (T1DM).Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance Prolonged exposure to insulin suppresses mitochondrial production in primary hepatocytes Inhibition of gluconeogenesis in primary hepatocytes by stromal cell-derived factor-1 (SDF-1) through a c-Src/Akt-dependent signaling pathway Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinase.Spatholobus suberectus Exhibits Antidiabetic Activity In Vitro and In Vivo through Activation of AKT-AMPK Pathway Cyclic AMP stimulates Mrp2 translocation by activating p38{alpha} MAPK in hepatic cells.Endoplasmic reticulum stress links hepatitis C virus RNA replication to wild-type PGC-1α/liver-specific PGC-1α upregulation MAPK signalling in cellular metabolism: stress or wellness?Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity Mapping MKP-3/FOXO1 interaction and evaluating the effect on gluconeogenesis.Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis.INTRACELLULAR SIGNALING BY BILE ACIDS.Phosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice.Relaxin activates peroxisome proliferator-activated receptor γ (PPARγ) through a pathway involving PPARγ coactivator 1α (PGC1α)Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism.Hypoxia-induced inflammatory cytokine secretion in human adipose tissue stromovascular cells.Effect of exercise on mouse liver and brain bioenergetic infrastructures Anti-diabetic effect of sorghum extract on hepatic gluconeogenesis of streptozotocin-induced diabetic rats.D-Xylose as a sugar complement regulates blood glucose levels by suppressing phosphoenolpyruvate carboxylase (PEPCK) in streptozotocin-nicotinamide-induced diabetic rats and by enhancing glucose uptake in vitro.Antidiabetic effects of pterosin A, a small-molecular-weight natural product, on diabetic mouse models Suppression of hepatic glucose production by human neutrophil alpha-defensins through a signaling pathway distinct from insulin.Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2.Insulin-like stimulation of cardiac fuel metabolism by physiological levels of glucagon: involvement of PI3K but not cAMP Impact of oxidative stress and peroxisome proliferator-activated receptor gamma coactivator-1alpha in hepatic insulin resistance.Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells.p38 MAPK α and β isoforms differentially regulate plasma membrane localization of MRP2.Multiple effects of acetaminophen and p38 inhibitors: towards pathway toxicology.

P2860

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P2860

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

http://www.wikidata.org/entity/Q33226681

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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name

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

@ast

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

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type

label

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

@ast

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

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prefLabel

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

@ast

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

@en

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Journal of Biological Chemistry

P1476

p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.

@en

P2093

Edgar G Lupo

http://www.w3.org/2001/XMLSchema#string

Jacques Robidoux

http://www.w3.org/2001/XMLSchema#string

Kiefer W Daniel

http://www.w3.org/2001/XMLSchema#string

Lisa Floering

http://www.w3.org/2001/XMLSchema#string

Qu Fan Collins

http://www.w3.org/2001/XMLSchema#string

Sheila Collins

http://www.w3.org/2001/XMLSchema#string

Thomas C Becker

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Wenhong Cao

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Yan Xiong

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P2860

Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

Activating transcription factor-2 mediates transcriptional regulation of gluconeogenic gene PEPCK by retinoic acid

Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

Nuclear magnetic resonance studies of hepatic glucose metabolism in humans.

beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase.

p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene

Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes.

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42731-42737

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scholarly article

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10.1074/JBC.M506223200

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P433

52

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280

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2005-11-03T00:00:00Z

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7496256

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16272151

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