Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of age-related cortical cataract in mice.
about
The LEGSKO mouse: a mouse model of age-related nuclear cataract based on genetic suppression of lens glutathione synthesisExpression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lensA method for determining cell number in the undisturbed epithelium of the mouse lens.Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression.Polymorphisms of DNA repair genes OGG1 and XPD and the risk of age-related cataract in Egyptians.X-ray induced cataract is preceded by LEC loss, and coincident with accumulation of cortical DNA, and ROS; similarities with age-related cataracts.Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lensSuppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cellsPolymorphisms in two DNA repair genes (XPD and XRCC1)--association with age related cataractsLens fibre cell differentiation and organelle loss: many paths lead to clarity.Age-related retention of fiber cell nuclei and nuclear fragments in the lens cortices of multiple species.Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract.Association of OGG1 and MTHFR polymorphisms with age-related cataract: A systematic review and meta-analysis.Senile cataract and genetic polymorphisms of APE1, XRCC1 and OGG1Genetic polymorphisms of HSP70 in age-related cataract.Apoptosis gene profiling reveals spatio-temporal regulated expression of the p53/Mdm2 pathway during lens developmentDeoxyribonucleic acid repair gene X-ray repair cross-complementing group 1 polymorphisms and non-carcinogenic disease risk in different populations: A meta-analysis.Association between DNA repair genes (XPD and XRCC1) polymorphisms and susceptibility to age-related cataract (ARC): a meta-analysis.Association between the 8-oxoguanine DNA glycosylase gene Ser326Cys polymorphism and age-related cataract: a systematic review and meta-analysis.Lens ER-stress response during cataract development in Mip-mutant mice.Autophagy and mitophagy participate in ocular lens organelle degradation.Lens density tracking in mice by Scheimpflug imaging.Mitochondria-Targeted Antioxidant Peptide SS31 Protects Cultured Human Lens Epithelial Cells against Oxidative Stress.β-amyloid expression in age-related cataract lens epithelia and the effect of β-amyloid on oxidative damage in human lens epithelial cells.Mitochondria induce oxidative stress, generation of reactive oxygen species and redox state unbalance of the eye lens leading to human cataract formation: disruption of redox lens organization by phospholipid hydroperoxides as a common basis for catThe changes of 8-OHdG, hOGG1, APE1 and Pol β in lenses of patients with age-related cataract.
P2860
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P2860
Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of age-related cortical cataract in mice.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Accumulation of DNA, nuclear a ...... ted cortical cataract in mice.
@ast
Accumulation of DNA, nuclear a ...... ted cortical cataract in mice.
@en
type
label
Accumulation of DNA, nuclear a ...... ted cortical cataract in mice.
@ast
Accumulation of DNA, nuclear a ...... ted cortical cataract in mice.
@en
prefLabel
Accumulation of DNA, nuclear a ...... ted cortical cataract in mice.
@ast
Accumulation of DNA, nuclear a ...... ted cortical cataract in mice.
@en
P2093
P356
P1476
Accumulation of DNA, nuclear a ...... ted cortical cataract in mice.
@en
P2093
Daniel Possin
Norman Wolf
Philip Penn
William Pendergrass
P304
P356
10.1167/IOVS.05-0808
P407
P577
2005-12-01T00:00:00Z