Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis.
about
Diversity-oriented synthetic strategies applied to cancer chemical biology and drug discoveryA nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injuryApaf-1 inhibitors protect from unwanted cell death in in vivo models of kidney ischemia and chemotherapy induced ototoxicityTyrosine phosphorylation turns alkaline transition into a biologically relevant process and makes human cytochrome c behave as an anti-apoptotic switch.A polymeric nanomedicine diminishes inflammatory events in renal tubular cellsPositional Scanning Synthesis of a Peptoid Library Yields New Inducers of Apoptosis that Target Karyopherins and Tubulin.Regioselective Synthesis of a Family of β-Lactams Bearing a Triazole Moiety as Potential Apoptosis InhibitorsThe apoptosome: emerging insights and new potential targets for drug designPolymer-drug conjugates as modulators of cellular apoptosis.Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.Caspases as therapeutic targets.The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identificationStructure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function.Molecules that modulate Apaf-1 activity.Apaf1 inhibition promotes cell recovery from apoptosis.NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cellsHMGN5 knockdown sensitizes prostate cancer cells to ionizing radiation.Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells.Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1.Inhibiting the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway with a regulator of calcineurin-derived peptide without affecting general calcineurin phosphatase activity.Caspase-3 gene transfected with LIGHT gene: can it be used for therapy of human hepatocellular carcinoma?Polypeptide modulators of caspase recruitment domain (CARD)-CARD-mediated protein-protein interactions.Apoptotic Protease Activating Factor-1 Inhibitor Mitigates Myocardial Ischemia Injury via Disturbing Procaspase-9 Recruitment by Apaf-1.Polypeptoids: A perfect match for molecular definition and macromolecular engineering?Efficient Synthesis of Conformationally Restricted Apoptosis Inhibitors Bearing a Triazole MoietyChemical Modulation of Peptoids: Synthesis and Conformational Studies on Partially Constrained Derivatives
P2860
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P2860
Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Small molecule inhibitors of A ...... chondrial-dependent apoptosis.
@ast
Small molecule inhibitors of A ...... chondrial-dependent apoptosis.
@en
type
label
Small molecule inhibitors of A ...... chondrial-dependent apoptosis.
@ast
Small molecule inhibitors of A ...... chondrial-dependent apoptosis.
@en
prefLabel
Small molecule inhibitors of A ...... chondrial-dependent apoptosis.
@ast
Small molecule inhibitors of A ...... chondrial-dependent apoptosis.
@en
P2093
P2860
P356
P1476
Small molecule inhibitors of A ...... chondrial-dependent apoptosis.
@en
P2093
Fearnhead HO
Ferrer-Montiel A
Messeguer A
Mingarro I
Pérez-Payá E
Sanclimens G
P2860
P2888
P304
P356
10.1038/SJ.CDD.4401828
P577
2005-12-09T00:00:00Z
P5875
P6179
1005096590