Nucleotide sequence and DNA secondary structure, as well as replication protein A, modulate the single-stranded abasic endonuclease activity of APE1.
about
APE1 incision activity at abasic sites in tandem repeat sequencesCritical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures.The many functions of APE1/Ref-1: not only a DNA repair enzymeEffect of the multifunctional proteins RPA, YB-1, and XPC repair factor on AP site cleavage by DNA glycosylase NEIL1.The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structuresAPE1, the DNA base excision repair protein, regulates the removal of platinum adducts in sensory neuronal cultures by NERDNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonucleaseDoes DNA repair occur during somatic hypermutation?Human abasic endonuclease action on multilesion abasic clusters: implications for radiation-induced biological damage.Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision.SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements.Mechanism of R-loop formation at immunoglobulin class switch sequences.Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).Inhibition of abasic site cleavage in bubble DNA by multifunctional protein YB-1.Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human.
P2860
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P2860
Nucleotide sequence and DNA secondary structure, as well as replication protein A, modulate the single-stranded abasic endonuclease activity of APE1.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Nucleotide sequence and DNA se ...... endonuclease activity of APE1.
@ast
Nucleotide sequence and DNA se ...... endonuclease activity of APE1.
@en
type
label
Nucleotide sequence and DNA se ...... endonuclease activity of APE1.
@ast
Nucleotide sequence and DNA se ...... endonuclease activity of APE1.
@en
prefLabel
Nucleotide sequence and DNA se ...... endonuclease activity of APE1.
@ast
Nucleotide sequence and DNA se ...... endonuclease activity of APE1.
@en
P356
P1476
Nucleotide sequence and DNA se ...... endonuclease activity of APE1
@en
P2093
David M Wilson
Jinshui Fan
P304
P356
10.1074/JBC.M511004200
P407
P577
2005-12-14T00:00:00Z