Expression of a Porphyromonas gingivalis lipid A palmitylacyltransferase in Escherichia coli yields a chimeric lipid A with altered ability to stimulate interleukin-8 secretion.
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The outer membrane protein LptO is essential for the O-deacylation of LPS and the co-ordinated secretion and attachment of A-LPS and CTD proteins in Porphyromonas gingivalis.Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid heterogeneity in Porphyromonas gingivalis.Manipulation of Neutrophils by Porphyromonas gingivalis in the Development of Periodontitis.Differential host response to LPS variants in amniochorion and the TLR4/MD-2 system in Macaca nemestrina.The lipid A phosphate position determines differential host Toll-like receptor 4 responses to phylogenetically related symbiotic and pathogenic bacteria.The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts.Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-κB signal transduction cascade and immuno-inflammatory response in human gingival fibroblastsFatty acid profiles in smokers with chronic periodontitis.Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepaciaIL-1R/TLR2 through MyD88 Divergently Modulates Osteoclastogenesis through Regulation of Nuclear Factor of Activated T Cells c1 (NFATc1) and B Lymphocyte-induced Maturation Protein-1 (Blimp1).Role of the innate immune system in host defence against bacterial infections: focus on the Toll-like receptors.The structurally similar, penta-acylated lipopolysaccharides of Porphyromonas gingivalis and Bacteroides elicit strikingly different innate immune responses.Antimicrobial peptides and nitric oxide production by neutrophils from periodontitis subjects.Reviewing and identifying amino acids of human, murine, canine and equine TLR4 / MD-2 receptor complexes conferring endotoxic innate immunity activation by LPS/lipid A, or antagonistic effects by Eritoran, in contrast to species-dependent modulationBiosynthetically engineered lipopolysaccharide as vaccine adjuvant.Microbiome and chronic inflammatory bowel diseases.Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship.Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity differentially modulates the expression of IL-6 and IL-8 in human gingival fibroblasts.Bacterial periplasmic oxido-reductases are essential for the activity of oxidized human antimicrobial β-defensin 1.
P2860
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P2860
Expression of a Porphyromonas gingivalis lipid A palmitylacyltransferase in Escherichia coli yields a chimeric lipid A with altered ability to stimulate interleukin-8 secretion.
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2006 թվականի հունվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
Expression of a Porphyromonas ...... ulate interleukin-8 secretion.
@ast
Expression of a Porphyromonas ...... ulate interleukin-8 secretion.
@en
type
label
Expression of a Porphyromonas ...... ulate interleukin-8 secretion.
@ast
Expression of a Porphyromonas ...... ulate interleukin-8 secretion.
@en
prefLabel
Expression of a Porphyromonas ...... ulate interleukin-8 secretion.
@ast
Expression of a Porphyromonas ...... ulate interleukin-8 secretion.
@en
P2093
P2860
P1476
Expression of a Porphyromonas ...... ulate interleukin-8 secretion.
@en
P2093
Brian W Bainbridge
Richard P Darveau
Robert A Reife
Stephen R Coats
Thu-Thao T Pham
P2860
P304
P356
10.1111/J.1462-5822.2005.00605.X
P577
2006-01-01T00:00:00Z