A high-throughput cell-based assay for inhibitors of ABCG2 activity. - Wikidata - wikimedia - TriplyDB

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

http://www.wikidata.org/entity/Q33234390

about

Discovery and resupply of pharmacologically active plant-derived natural products: A review A novel two mode-acting inhibitor of ABCG2-mediated multidrug transport and resistance in cancer chemotherapy A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery Screening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interference Knocking down breast cancer resistance protein (Bcrp) by adenoviral vector-mediated RNA interference (RNAi) in sandwich-cultured rat hepatocytes: a novel tool to assess the contribution of Bcrp to drug biliary excretion New inhibitors of ABCG2 identified by high-throughput screening Botryllamides: natural product inhibitors of ABCG2 Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay.Synthesis and structure-activity relationship of botryllamides that block the ABCG2 multidrug transporter Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells.Inhibition of ABCG2-mediated drug efflux by naphthopyrones from marine crinoids.Dissecting variability in responses to cancer chemotherapy through systems pharmacology.Lamellarins as inhibitors of P-glycoprotein-mediated multidrug resistance in a human colon cancer cell line.Kinase inhibitor scaffolds against neurodegenerative diseases from a Southern Australian ascidian, Didemnum sp.ABCG2 regulated by MAPK pathways is associated with cancer progression in laryngeal squamous cell carcinoma.A high-content assay strategy for the identification and profiling of ABCG2 modulators in live cells.WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells.Oligomycins as inhibitors of K-Ras plasma membrane localisation.Discovering natural product modulators to overcome multidrug resistance in cancer chemotherapy.Targeted therapy for cancer stem cells: the patched pathway and ABC transporters.Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges.Matching the power of high throughput screening to the chemical diversity of natural products Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2 ABCG2: the key to chemoresistance in cancer stem cells?Do stem-like cells play a role in drug resistance of sarcomas?Hepatic cancer stem cells and drug resistance: Relevance in targeted therapies for hepatocellular carcinoma.The biological implication of cancer stem cells in hepatocellular carcinoma: a possible target for future therapy.An evidence-based systematic review of chlorophyll by the Natural Standard Research Collaboration.Nature and uses of fluorescent dyes for drug transporter studies.Natural products for human health: an historical overview of the drug discovery approaches.Modulating the function of ATP-binding cassette subfamily G member 2 (ABCG2) with inhibitor cabozantinib.Aurones as modulators of ABCG2 and ABCB1: synthesis and structure-activity relationships.Amycolatopsins A-C: antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494.Dacomitinib potentiates the efficacy of conventional chemotherapeutic agents via inhibiting the drug efflux function of ABCG2 in vitro and in vivo.Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.ATP Binding Cassette Sub-family Member 2 (ABCG2) and Xenobiotic Exposure During Early Mouse Embryonic Stem Cell Differentiation.Multidrug-resistant transporter expression does not always result in drug resistance The Effects of Synthetically Modified Natural Compounds on ABC Transporters

P2860

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P2860

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

http://www.wikidata.org/entity/Q33234390

description

2006 nî lūn-bûn

@nan

2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2006年の論文

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2006年論文

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2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

@ast

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

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type

label

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

@ast

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

@en

prefLabel

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

@ast

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

@en

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P1433

Journal of Biomolecular Screening

P1476

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

@en

P2093

Curtis J Henrich

http://www.w3.org/2001/XMLSchema#string

Ekaterina I Goncharova

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Heidi R Bokesch

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James B McMahon

http://www.w3.org/2001/XMLSchema#string

Jennifer A Wilson

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Susan E Bates

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P2860

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

The human ATP-binding cassette (ABC) transporter superfamily

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Tumour stem cells and drug resistance

Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2).

ABCG2 (BCRP) expression in normal and malignant hematopoietic cells.

Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.

VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

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176-183

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scholarly article

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10.1177/1087057105284576

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2

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7286027

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16490770

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