Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges.
about
DIPG in Children - What Can We Learn from the Past?Where is it and How Does it Get There - Intracellular Localization and Traffic of P-glycoproteinEZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumorsAnticancer efficacy of a nitric oxide-modified derivative of bifendate against multidrug-resistant cancer cellsPrediction of promiscuous p-glycoprotein inhibition using a novel machine learning schemeIn vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine gliomabba, a synthetic derivative of 23-hydroxybutulinic acid, reverses multidrug resistance by inhibiting the efflux activity of MRP7 (ABCC10)In silico prediction of inhibition of promiscuous breast cancer resistance protein (BCRP/ABCG2)Multifunctional polymeric micelles for delivery of drugs and siRNA.Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics.The siRNA targeted to mdr1b and mdr1a mRNAs in vivo sensitizes murine lymphosarcoma to chemotherapyRole and mechanism of Twist1 in modulating the chemosensitivity of FaDu cells.Cell-penetrating, guanidinium-rich molecular transporters for overcoming efflux-mediated multidrug resistance.A combination of curcumin with either gramicidin or ouabain selectively kills cells that express the multidrug resistance-linked ABCG2 transporterSchistosome ABC multidrug transporters: From pharmacology to physiology.Imaging of multidrug resistance in cancerInteractions of the multidrug resistance modulators tariquidar and elacridar and their analogues with P-glycoprotein.Hydrogel-assisted functional reconstitution of human P-glycoprotein (ABCB1) in giant liposomes.Pharmacology and potential physiological significance of schistosome multidrug resistance transportersβ-arrestin 2 is associated with multidrug resistance in breast cancer cells through regulating MDR1 gene expressionDiscovering natural product modulators to overcome multidrug resistance in cancer chemotherapy.Improving cancer chemotherapy with modulators of ABC drug transporters.A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy.Formation of spherical cancer stem-like cell colonies with resistance to chemotherapy drugs in the human malignant fibrous histiocytoma NMFH-1 cell lineOvercoming multidrug-resistance in vitro and in vivo using the novel P-glycoprotein inhibitor 1416Afatinib reverses multidrug resistance in ovarian cancer via dually inhibiting ATP binding cassette subfamily B member 1.Overexpression of ATP-binding cassette transporter ABCG2 as a potential mechanism of acquired resistance to vemurafenib in BRAF(V600E) mutant cancer cells.Drug-protein hydrogen bonds govern the inhibition of the ATP hydrolysis of the multidrug transporter P-glycoproteinAdvances in PET imaging of P-glycoprotein function at the blood-brain barrier.Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletionABC multidrug transporters in schistosomes and other parasitic flatwormsIn vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs.Curcumin inhibits the activity of ABCG2/BCRP1, a multidrug resistance-linked ABC drug transporter in mice.Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2.Regression of prostate cancer xenografts by RLIP76 depletion.Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells.Impaired mitochondrial energy production and ABC transporter function-A crucial interconnection in dementing proteopathies of the brain.Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.Drug interactions at the blood-brain barrier: fact or fantasy?Design, synthesis, and biological evaluation of (S)-valine thiazole-derived cyclic and noncyclic peptidomimetic oligomers as modulators of human P-glycoprotein (ABCB1).
P2860
Q26777843-CD759F12-1D97-4C9D-8D53-2D3F76728F40Q27008624-9F3595D3-8B30-45FE-A942-B04DA1054DE1Q27318449-E5CB385D-9263-460E-ADF4-4E2ADAE14624Q28468523-AEFEFE74-2EE0-4EF0-93E7-EDA111189952Q28481547-A2CD5786-EDC0-4C38-BED1-6746CD1A1632Q28487205-EF390C28-EE87-470C-93A3-3C0B07D512BEQ28533538-E076ED18-9013-40B4-8444-474551BFC784Q28540667-D867E824-44AA-4F2A-9454-6C5D071BA313Q30438973-03DB647D-F690-4243-9A92-8E2B2347426BQ30636997-7A506B93-0081-417E-B966-42B466DD3E46Q33578222-54CC8A6C-4119-4011-BA50-522447652101Q33798970-3924A7F0-A442-45C6-8936-370135AEE1E8Q34011165-A24C002D-24C9-4287-BF4C-8C06A7E947E0Q34467622-4C7ED5CB-5DC0-491D-BD59-624CC75D4242Q34705514-7A56C1D7-DC34-41F3-A593-6CE7E2DBEB77Q34823564-2425AB0B-F14D-425E-9A9F-61AA2C3A7ADBQ34940694-9ECD8900-54A2-45AE-9ADF-0782C7DBFC7CQ35137117-071C97B5-7AEC-4F99-93F2-8462C28553BCQ35159499-CC097D70-581D-474C-BDC9-7B987F6BE528Q35406094-6A9C60F3-BB86-42E0-B23F-82B9CBA6C68DQ35915497-E73AA8F4-A305-4E1E-A8FE-E82FEA10F6C5Q36108251-777E4670-8364-477E-B09A-5823C026B62DQ36234061-E1D3A59B-7501-476B-ADC6-2FC42577FB89Q36334761-B07E47D9-7D61-487C-9394-31861F61B8CBQ36397699-65515A78-9AA7-4CE8-B1C1-40E0A6835F01Q36413392-E6A50FB0-F9BD-4519-8FB4-D7EEC0C07062Q36556926-521EE296-7BFF-4BA7-B820-F57EC2BCE084Q36578713-B0B47310-64E6-42F5-95C4-7591F34F840AQ36638627-EDCE7546-BCAF-4913-95B0-19AD667E8EC3Q36765399-C8122611-7A1B-4B67-ABA8-49DEDE63A571Q37053762-F83F70B2-16A8-4CBC-AADB-4E6F57D33194Q37070476-F372F7EC-C624-4699-98C5-35FB2F3678F5Q37143617-012D55FC-2AEE-4034-8ECF-5967DEEC983CQ37188016-D6D3618D-5E15-44EE-8C06-62F60FB4B20AQ37194622-A3A375FA-1012-4C46-9BF1-6EB2485E05FCQ37267975-445A5586-4F91-4644-A671-5DDE8CB9BC6DQ37351380-16E8CBDB-F7CC-4449-979B-A0867B660017Q37353400-0BC0F274-1432-4EC8-A331-55F2038E51EDQ37362486-BEF573BE-663F-4A69-8736-5A40E396259CQ37527758-8BEEA733-1DC7-4F3A-9F22-B2D8BEACA96A
P2860
Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Development of inhibitors of A ...... present status and challenges.
@en
Development of inhibitors of A ...... present status and challenges.
@nl
type
label
Development of inhibitors of A ...... present status and challenges.
@en
Development of inhibitors of A ...... present status and challenges.
@nl
prefLabel
Development of inhibitors of A ...... present status and challenges.
@en
Development of inhibitors of A ...... present status and challenges.
@nl
P2093
P2860
P356
P1476
Development of inhibitors of A ...... present status and challenges.
@en
P2093
Chung-Pu Wu
Suneet Shukla
Suresh V Ambudkar
P2860
P304
P356
10.1517/17425255.4.2.205
P407
P577
2008-02-01T00:00:00Z