Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities. - Wikidata - wikimedia - TriplyDB

Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities.

Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities.

http://www.wikidata.org/entity/Q33235638

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Structural basis for the recognition and cleavage of histone H3 by cathepsin L Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes Reaching the melting point: Degradative enzymes and protease inhibitors involved in baculovirus infection and dissemination IrAE – An asparaginyl endopeptidase (legumain) in the gut of the hard tick Ixodes ricinus Hemoglobin Digestion in Blood-Feeding Ticks: Mapping a Multipeptidase Pathway by Functional Proteomics Development of calpain-specific inactivators by screening of positional scanning epoxide libraries Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design Structural and Functional Relationships in the Virulence-associated Cathepsin L Proteases of the Parasitic Liver Fluke, Fasciola hepatica Cocrystal Structures of Primed Side-Extending α-Ketoamide Inhibitors Reveal Novel Calpain-Inhibitor Aromatic Interactions #Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interference SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni Proteomic analysis of human skin treated with larval schistosome peptidases reveals distinct invasion strategies among species of blood flukes Expression, characterization, and cellular localization of knowpains, papain-like cysteine proteases of the Plasmodium knowlesi malaria parasite Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence Blocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132 Mutation in the Pro-Peptide Region of a Cysteine Protease Leads to Altered Activity and Specificity-A Structural and Biochemical Approach A single diamagnetic catalyCEST MRI contrast agent that detects cathepsin B enzyme activity by using a ratio of two CEST signals A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.Covalent assembly of nanoparticles as a peptidase-degradable platform for molecular MRI.Aminopeptidase fingerprints, an integrated approach for identification of good substrates and optimal inhibitors.Self-assembled small-molecule microarrays for protease screening and profiling.Inhibitor fingerprinting of metalloproteases using microplate and microarray platforms: an enabling technology in Catalomics.Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L Using specificity to strategically target proteases.Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes).Quantitative and label-free technique for measuring protease activity and inhibition using a microfluidic cantilever array.Substrate specificity of transthyretin: identification of natural substrates in the nervous system.Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.Positional scanning synthetic combinatorial libraries for substrate profiling.Robust production of a peptide library using methodological synchronization A sequence and structure based method to predict putative substrates, functions and regulatory networks of endo proteases.Protease cleavage sites in HIV-1 gp120 recognized by antigen processing enzymes are conserved and located at receptor binding sites Characterization of proteinases from the midgut of Rhipicephalus (Boophilus) microplus involved in the generation of antimicrobial peptides.Biochemical characterization of Plasmodium falciparum dipeptidyl aminopeptidase 1 Computational study on substrate specificity of a novel cysteine protease 1 precursor from Zea mays Substrate specifity profiling of the Aspergillus fumigatus proteolytic secretome reveals consensus motifs with predominance of Ile/Leu and Phe/Tyr

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P2860

Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities.

http://www.wikidata.org/entity/Q33235638

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

Substrate profiling of cystein ...... tionally unique specificities.

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Substrate profiling of cystein ...... tionally unique specificities.

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Substrate profiling of cystein ...... tionally unique specificities.

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Substrate profiling of cystein ...... tionally unique specificities.

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Substrate profiling of cystein ...... tionally unique specificities.

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Substrate profiling of cystein ...... tionally unique specificities.

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P1433

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P1433

Journal of Biological Chemistry

P1476

Substrate profiling of cystein ...... tionally unique specificities.

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P2093

Charles S Craik

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Dieter Brömme

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Doron C Greenbaum

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Jonathan A Ellman

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Youngchool Choe

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P2860

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Lysosomal cysteine proteases: facts and opportunities.

Cluster analysis and display of genome-wide expression patterns

Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization

Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

Definition of the extended substrate specificity determinants for beta-tryptases I and II.

Cercarial elastase is encoded by a functionally conserved gene family across multiple species of schistosomes.

Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.

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12824-12832

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scholarly article

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10.1074/JBC.M513331200

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18

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281

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Fabien Lecaille

Francesco Leonetti

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2006-03-06T00:00:00Z

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7258458

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16520377

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