Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates
about
Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44Pro-urokinase-type plasminogen activator is a substrate for hepsinMatriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteinsRegulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in miceExpression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cellsAdhesion signaling by a novel mitotic substrate of src kinasesMatriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndromeMatriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivoThe epidermal barrier function is dependent on the serine protease CAP1/Prss8Regulation of feto-maternal barrier by matriptase- and PAR-2-mediated signaling is required for placental morphogenesis and mouse embryonic survivalCatalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinaseStructure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1A Reverse Binding Motif That Contributes to Specific Protease Inhibition by AntibodiesCrystal Structures of Matriptase in Complex with Its Inhibitor Hepatocyte Growth Factor Activator Inhibitor-1Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymesActivation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine proteaseTissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1Specificity of coagulation factor signalingThe activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitorBikunin target genes in ovarian cancer cells identified by microarray analysisSphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptaseInhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinaseAssembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contactsIdentification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasinReduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activationN-terminal processing is essential for release of epithin, a mouse type II membrane serine proteaseEvidence for the occurrence of membrane-type serine protease 1/matriptase on the basolateral sides of enterocytesRoles of functional and structural domains of hepatocyte growth factor activator inhibitor type 1 in the inhibition of matriptaseHepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placentaSerase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycansMouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissuesLaminin-332 cleavage by matriptase alters motility parameters of prostate cancer cells.From prediction to experimental validation: desmoglein 2 is a functionally relevant substrate of matriptase in epithelial cells and their reciprocal relationship is important for cell adhesion.Phage display substrate: a blind method for determining protease specificity.Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancersRegulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor.Protein interaction analysis of ST14 domains and their point and deletion mutants.Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities.
P2860
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P2860
Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Cellular localization of membr ...... inogen activator as substrates
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Cellular localization of membr ...... inogen activator as substrates
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Cellular localization of membr ...... inogen activator as substrates
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Cellular localization of membr ...... inogen activator as substrates
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Cellular localization of membr ...... inogen activator as substrates
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Cellular localization of membr ...... inogen activator as substrates
@en
Cellular localization of membr ...... inogen activator as substrates
@en-gb
Cellular localization of membr ...... inogen activator as substrates
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prefLabel
Cellular localization of membr ...... inogen activator as substrates
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Cellular localization of membr ...... inogen activator as substrates
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Cellular localization of membr ...... inogen activator as substrates
@en-gb
Cellular localization of membr ...... inogen activator as substrates
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P2093
P2860
P3181
P356
P1476
Cellular localization of membr ...... inogen activator as substrates
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P2093
P2860
P304
P3181
P356
10.1074/JBC.M002941200
P407
P577
2000-08-25T00:00:00Z