Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
about
P1343
Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndromeThe Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomesHOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitmentTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationConserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotesIn vivo stoichiometry of shelterin componentsInherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndromeOB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulationTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesFinding the end: recruitment of telomerase to telomeresTelomere dysfunction and chromosome instabilityTelomere protection by TPP1 is mediated by POT1a and POT1bTelomeres-structure, function, and regulationMultiple facets of TPP1 in telomere maintenanceProgressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cellsHow telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNASurvival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9.The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7Functional interaction between telomere protein TPP1 and telomeraseOligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardiansATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeresPOT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombinationEvolution of Arabidopsis protection of telomeres 1 alters nucleic acid recognition and telomerase regulationApollo contributes to G overhang maintenance and protects leading-end telomeresSingle strand DNA binding proteins 1 and 2 protect newly replicated telomeresSNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repairSuper-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formationMolecular Architecture of Full-length TRF1 Favors Its Interaction with DNAMultiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.Persistent telomere damage induces bypass of mitosis and tetraploidy.Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells.How telomeres solve the end-protection problem.Telomere protection by TPP1/POT1 requires tethering to TIN2Duplication and functional specialization of the telomere-capping protein Cdc13 in Candida speciesPot1a prevents telomere dysfunction and ATM-dependent neuronal loss.Tetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint.Telomere maintenance through spatial control of telomeric proteinsArabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance.Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.Pot1 and cell cycle progression cooperate in telomere length regulation.
P2860
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P2860
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
description
2006 nî lūn-bûn
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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Recent expansion of the telome ...... teins protect mouse telomeres.
@ast
Recent expansion of the telome ...... teins protect mouse telomeres.
@en
type
label
Recent expansion of the telome ...... teins protect mouse telomeres.
@ast
Recent expansion of the telome ...... teins protect mouse telomeres.
@en
prefLabel
Recent expansion of the telome ...... teins protect mouse telomeres.
@ast
Recent expansion of the telome ...... teins protect mouse telomeres.
@en
P1433
P1476
Recent expansion of the telome ...... teins protect mouse telomeres.
@en
P2093
Hiroyuki Takai
Jan-Peter Daniels
P356
10.1016/J.CELL.2006.04.044
P407
P4510
P577
2006-07-01T00:00:00Z