Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification.
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Can cytoplasmic nucleophosmin be detected by immunocytochemical staining of cell smears in acute myeloid leukemia?The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model.Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish.Cytoplasmic FANCA-FANCC complex interacts and stabilizes the cytoplasm-dislocalized leukemic nucleophosmin protein (NPMc)Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity.Monoclonal antibodies against nucleophosmin mutants: potentials for the detection of acute myeloid leukemia.Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in miceTWIST-1 promotes cell growth, drug resistance and progenitor clonogenic capacities in myeloid leukemia and is a novel poor prognostic factor in acute myeloid leukemiaDiagnosis of acute myeloid leukemia according to the WHO classification in the Japan Adult Leukemia Study Group AML-97 protocolNucleophosmin Mutants Promote Adhesion, Migration and Invasion of Human Leukemia THP-1 Cells through MMPs Up-regulation via Ras/ERK MAPK SignalingIn vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG miceGenetics of therapy-related myelodysplasia and acute myeloid leukemia.A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysisAltered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.Role of nucleophosmin in acute myeloid leukemia.NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia.Acute myeloid leukemia: advances in diagnosis and classification.Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.Mutations inDNMT3A and loss of RKIP are independent events in acute monocytic leukemia.Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.Biological and clinical consequences of NPM1 mutations in AML.Nucleophosmin/B26 regulates PTEN through interaction with HAUSP in acute myeloid leukemia.A surrogate marker to detect nucleophosnim (NPM1) gene mutations in the cytoplasm of acute myeloid leukemia (AML) blast cells in 30 adult Iraqi patients.Hepatocyte odd protein shuttling (HOPS) is a bridging protein in the nucleophosmin-p19 Arf network.Molecular and alternative methods for diagnosis of acute myeloid leukemia with mutated NPM1: flexibility may help.Cytoplasmic nucleophosmin is not detected in blastic plasmacytoid dendritic cell neoplasm.Clonal heterogeneity in patients with cytogenetically normal acute myeloid leukemia with NPM1 mutations.Molecular Analysis of Gene Rearrangements and Mutations in Acute Leukemias and Myeloid Neoplasms.NPM1 mutations may reveal acute myeloid leukemia in cases otherwise morphologically diagnosed as myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms.Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias
P2860
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P2860
Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification.
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2006 nî lūn-bûn
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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mutated nucleophosmin detects ...... Impact on WHO classification.
@ast
Mutated nucleophosmin detects ...... Impact on WHO classification.
@en
Mutated nucleophosmin detects ...... Impact on WHO classification.
@nl
type
label
Mutated nucleophosmin detects ...... Impact on WHO classification.
@ast
Mutated nucleophosmin detects ...... Impact on WHO classification.
@en
Mutated nucleophosmin detects ...... Impact on WHO classification.
@nl
prefLabel
Mutated nucleophosmin detects ...... Impact on WHO classification.
@ast
Mutated nucleophosmin detects ...... Impact on WHO classification.
@en
Mutated nucleophosmin detects ...... Impact on WHO classification.
@nl
P2093
P50
P1433
P1476
Mutated nucleophosmin detects ...... Impact on WHO classification.
@en
P2093
Alessandra Pucciarini
Alessia Tabarrini
Arcangelo Liso
Barbara Bigerna
Cristina Mecucci
Enrico Tiacci
Franco Mandelli
Giovanna Meloni
Ildo Nicoletti
Manola Carini
P304
P356
10.1182/BLOOD-2006-06-026716
P407
P577
2006-08-22T00:00:00Z