NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.
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Tyrosine kinase inhibitors targeting FLT3 in the treatment of acute myeloid leukemia.The Biology and Targeting of FLT3 in Pediatric Leukemia.Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance.Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model.Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.FLT3 dancing on the stem cell.Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.Knock-in of the R394W mutation causes MDS and cooperates with to drive aggressive myeloid neoplasms in mice
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NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
NPMc+ cooperates with Flt3/ITD ...... recapitulating human disease.
@en
NPMc+ cooperates with Flt3/ITD ...... recapitulating human disease.
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type
label
NPMc+ cooperates with Flt3/ITD ...... recapitulating human disease.
@en
NPMc+ cooperates with Flt3/ITD ...... recapitulating human disease.
@nl
prefLabel
NPMc+ cooperates with Flt3/ITD ...... recapitulating human disease.
@en
NPMc+ cooperates with Flt3/ITD ...... recapitulating human disease.
@nl
P2093
P2860
P50
P1476
NPMc+ cooperates with Flt3/ITD ...... recapitulating human disease.
@en
P2093
Amy S Duffield
Colleen Annesley
Daniel Magoon
David Huso
Donald Small
Emily McIntyre
Markus Reschke
Patrick Brown
Sarah Greenblatt
P2860
P304
P356
10.1016/J.EXPHEM.2013.10.005
P577
2013-10-29T00:00:00Z