Development and application of a high-throughput assay for glmS riboswitch activators.
about
Prospects for riboswitch discovery and analysisStructure-guided design of fluorescent S-adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAsThe glmS ribozyme: use of a small molecule coenzyme by a gene-regulatory RNAStudying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic DystrophyRecent Progress in Nucleic Acid Aptamer-Based Biosensors and Bioassays.Assay for glucosamine 6-phosphate using a ligand-activated ribozyme with fluorescence resonance energy transfer or CE-laser-induced fluorescence detection.Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora.Engineered allosteric ribozymes that sense the bacterial second messenger cyclic diguanosyl 5'-monophosphate.Identification of ligand analogues that control c-di-GMP riboswitches.Deciphering the role of glucosamine-6-phosphate in the riboswitch action of glmS ribozymeRiboswitches as antibacterial drug targets.Programmable and automated bead-based microfluidics for versatile DNA microarrays under isothermal conditions.Riboswitches: discovery of drugs that target bacterial gene-regulatory RNAs.Fluorescence monitoring of riboswitch transcription regulation using a dual molecular beacon assayLeakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme.Computational selection and experimental validation of allosteric ribozymes that sense a specific sequence of human telomerase reverse transcriptase mRNAs as universal anticancer therapy agentsStrategies for the design of RNA-binding small molecules.New insights into riboswitch regulation mechanisms.Riboswitch-based antibacterial drug discovery using high-throughput screening methods.The Emerging Role of RNA as a Therapeutic Target for Small Molecules.Designing drugs that overcome antibacterial resistance: where do we stand and what should we do?An in vivo high-throughput screening for riboswitch ligands using a reverse reporter gene system.Examination of the structural and functional versatility of glmS ribozymes by using in vitro selectionRNA-mediated signal perception in pathogenic bacteria.Conformational changes in the expression domain of the Escherichia coli thiM riboswitch.Mechanism and distribution of glmS ribozymes.Ligand design for riboswitches, an emerging target class for novel antibiotics.Fluoro-Carba-Sugars are Glycomimetic Activators of the glmS Ribozyme.Bacterial Riboswitch Discovery and Analysis
P2860
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P2860
Development and application of a high-throughput assay for glmS riboswitch activators.
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Development and application of a high-throughput assay for glmS riboswitch activators.
@ast
Development and application of a high-throughput assay for glmS riboswitch activators.
@en
Development and application of a high-throughput assay for glmS riboswitch activators.
@nl
type
label
Development and application of a high-throughput assay for glmS riboswitch activators.
@ast
Development and application of a high-throughput assay for glmS riboswitch activators.
@en
Development and application of a high-throughput assay for glmS riboswitch activators.
@nl
prefLabel
Development and application of a high-throughput assay for glmS riboswitch activators.
@ast
Development and application of a high-throughput assay for glmS riboswitch activators.
@en
Development and application of a high-throughput assay for glmS riboswitch activators.
@nl
P2093
P356
P1433
P1476
Development and application of a high-throughput assay for glmS riboswitch activators.
@en
P2093
Izabela Puskarz
Kenneth Blount
Robert Penchovsky
Ronald Breaker
P356
10.4161/RNA.3.2.3102
P577
2006-04-14T00:00:00Z