Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides. - Wikidata - wikimedia - TriplyDB

Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides.

Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides.

http://www.wikidata.org/entity/Q33267088

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Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discovery Mitochondrial targeting of electron scavenging antioxidants: regulation of selective oxidation vs random chain reactions Mitochondria targeting of non-peroxidizable triphenylphosphonium conjugated oleic acid protects mouse embryonic cells against apoptosis: role of cardiolipin remodeling Effects of tempol and redox-cycling nitroxides in models of oxidative stress.PGC-1α, mitochondrial dysfunction, and Huntington's disease Mitochondria as a target in treatment Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents.Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis--there is nothing more practical than a good theory Strategies for discovery of small molecule radiation protectors and radiation mitigators Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogs The zebrafish--Danio rerio--is a useful model for measuring the effects of small-molecule mitigators of late effects of ionizing irradiation Two strategies for the development of mitochondrion-targeted small molecule radiation damage mitigators Pharmacological mitigation of tissue damage during brain microdialysis A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells Genetically encoded redox sensor identifies the role of ROS in degenerative and mitochondrial disease pathogenesis A review of the effects of FSCV and microdialysis measurements on dopamine release in the surrounding tissue Antioxidant Approaches to Management of Ionizing Irradiation Injury Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres Impact of Antioxidants on Cardiolipin Oxidation in Liposomes: Why Mitochondrial Cardiolipin Serves as an Apoptotic Signal?Mitochondrial function in hypoxic ischemic injury and influence of aging Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation Effectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation Mitigators A mitochondria-targeted triphenylphosphonium-conjugated nitroxide functions as a radioprotector/mitigator.Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.Targeted delivery of radioprotective agents to mitochondria Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential Targeting antioxidant and antithrombotic biotherapeutics to endothelium.Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.Intraesophageal administration of GS-nitroxide (JP4-039) protects against ionizing irradiation-induced esophagitis A mitochondria-targeted nitroxide/hemigramicidin S conjugate protects mouse embryonic cells against gamma irradiation.Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO(.) and protects mouse embryonic cells against irradiation-induced apoptosis Radiation countermeasure agents: an update.Nitroxides: applications in synthesis and in polymer chemistry.Prospects for neuroprotective therapies in prodromal Huntington's disease.

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P2860

Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides.

http://www.wikidata.org/entity/Q33267088

description

2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Structural requirements for op ...... tivity of targeted nitroxides.

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Structural requirements for op ...... tivity of targeted nitroxides.

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Structural requirements for op ...... tivity of targeted nitroxides.

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Structural requirements for op ...... tivity of targeted nitroxides.

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JPET.106.114769

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Journal of Pharmacology and Experimental Therapeutics

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Structural requirements for op ...... tivity of targeted nitroxides.

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Igor Kurnikov

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Jianfei Jiang

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Jingbo Xiao

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Joel S Greenberger

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Mitchell P Fink

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Natalia A Belikova

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Qing Zhao

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Rebecca Braslau

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Valerian E Kagan

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1050-1060

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scholarly article

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10.1124/JPET.106.114769

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320

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Andrew A. Amoscato

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6621699

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