F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses. - Wikidata - wikimedia - TriplyDB

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.

http://www.wikidata.org/entity/Q33267512

about

A conditional knockout resource for the genome-wide study of mouse gene function Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs Multiple knockout mouse models reveal lincRNAs are required for life and brain development Highly efficient generation of biallelic reporter gene knock-in mice via CRISPR-mediated genome editing of ESCs Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis Conditionals by inversion provide a universal method for the generation of conditional alleles The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.Comparative genetic analysis: the utility of mouse genetic systems for studying human monogenic disease.BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.Effect of stem cell activation, culture media of manipulated embryos, and site of embryo transfer in the production of F0 embryonic stem cell mice.Production of mouse chimeras by injection of embryonic stem cells into the perivitelline space of one-cell stage embryos.Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos.Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.Next-generation mammalian genetics toward organism-level systems biology Tetraploid embryonic stem cells can contribute to the development of chimeric fetuses and chimeric extraembryonic tissues The many faces of Pluripotency: in vitro adaptations of a continuum of in vivo states.Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells.Phenotypic annotation of the mouse X chromosome Modelling human regulatory variation in mouse: finding the function in genome-wide association studies and whole-genome sequencing HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst.The birth of embryonic pluripotency.Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo Rescue of germline transmission from chimeras by IVF after sperm analysis.Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos.Germline competence of mouse ES and iPS cell lines: Chimera technologies and genetic background.Association of telomere length with authentic pluripotency of ES/iPS cells Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection Establishment of epigenetic patterns in development Optimization of protocols for derivation of mouse embryonic stem cell lines from refractory strains, including the non obese diabetic mouse Comparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts.Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.Efficient production of chimeric mice from embryonic stem cells injected into 4- to 8-cell and blastocyst embryos Erythropoiesis in the absence of adult hemoglobin.

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F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.

http://www.wikidata.org/entity/Q33267512

description

2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

F0 generation mice fully deriv ...... immediate phenotypic analyses.

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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type

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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Nature Biotechnology

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F0 generation mice fully deriv ...... immediate phenotypic analyses.

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P2093

Anthony T Doré

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David M Valenzuela

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George D Yancopoulos

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Jennifer M Escaravage

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Joseph F Hickey

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Lakeisha Esau

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Melissa G Dominguez

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Nicholas W Gale

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Niels C Adams

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Sean Stevens

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scholarly article

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10.1038/NBT1263

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1

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25

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David Frendewey

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2006-12-24T00:00:00Z

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6613523

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17187059

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