CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.
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Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsIn vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administrationEvaluation of immunological escape mechanisms in a mouse model of colorectal liver metastases.Intratumoral FoxP3+Helios+ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer.In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunctionIntraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinomaTumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice.p53MVA therapy in patients with refractory gastrointestinal malignancies elevates p53-specific CD8+ T-cell responsesAccumulation of CCR4⁺CTLA-4 FOXP3⁺CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cellsExpression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance.Analysis of FoxP3+ T-regulatory cells and CD8+ T-cells in ovarian carcinoma: location and tumor infiltration patterns are key prognostic markers.Regulatory T lymphocytes are associated with less aggressive histologic features in microsatellite-unstable colorectal cancers.CD4(+)CD62L(+) central memory T cells can be converted to Foxp3(+) T cells.Cancer immunotherapy: the role regulatory T cells play and what can be done to overcome their inhibitory effects.An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinomaZileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammationT cell subpopulations in lymph nodes may not be predictive of patient outcome in colorectal cancerAssessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer.A distinct chemokine axis does not account for enrichment of Foxp3(+) CD4(+) T cells in carcinogen-induced fibrosarcomas.Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiationT cells and adoptive immunotherapy: recent developments and future prospects in gastrointestinal oncology.A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.Suppression of tumour-specific CD4⁺ T cells by regulatory T cells is associated with progression of human colorectal cancerImmunotherapy of Metastatic Colorectal Cancer: Prevailing Challenges and New Perspectives.Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determinated by multiparametric single cell mass cytometry analysis.Prognostic value of innate and adaptive immunity in colorectal cancer.The impact of regulatory T cells on carcinogen-induced sarcogenesisTumor-released survivin induces a type-2 t cell response and decreases cytotoxic T cell function, in vitro.Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer.Tumor-infiltrating immune cells: triggers for tumor capsule disruption and tumor progression?Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instabilityRegulatory T cells and tumour immunity - observations in mice and men.Immune cells in colorectal cancer: prognostic relevance and therapeutic strategies.Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness.NF-κB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cellsRegulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancerTargeting cytochrome P450 CYP1B1 with a therapeutic cancer vaccine.Positive and negative influences of regulatory T cells on tumour immunity.Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma.
P2860
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P2860
CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.
@ast
CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.
@en
type
label
CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.
@ast
CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.
@en
prefLabel
CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.
@ast
CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.
@en
P2093
P2860
P1433
P1476
CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.
@en
P2093
Andrea Plant
Andrew J Godkin
Brian I Rees
Gareth J Betts
Geraint T Williams
Jared Torkington
Kate L Wright
Richard Harrop
Sarah L Clarke
Tariq M El-Shanawany
P2860
P356
10.1371/JOURNAL.PONE.0000129
P407
P577
2006-12-27T00:00:00Z