CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. - Wikidata - wikimedia - TriplyDB

CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.

CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.

http://www.wikidata.org/entity/Q33268298

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Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units In vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration Evaluation of immunological escape mechanisms in a mouse model of colorectal liver metastases.Intratumoral FoxP3+Helios+ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer.In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice.p53MVA therapy in patients with refractory gastrointestinal malignancies elevates p53-specific CD8+ T-cell responses Accumulation of CCR4⁺CTLA-4 FOXP3⁺CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cells Expression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance.Analysis of FoxP3+ T-regulatory cells and CD8+ T-cells in ovarian carcinoma: location and tumor infiltration patterns are key prognostic markers.Regulatory T lymphocytes are associated with less aggressive histologic features in microsatellite-unstable colorectal cancers.CD4(+)CD62L(+) central memory T cells can be converted to Foxp3(+) T cells.Cancer immunotherapy: the role regulatory T cells play and what can be done to overcome their inhibitory effects.An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation T cell subpopulations in lymph nodes may not be predictive of patient outcome in colorectal cancer Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer.A distinct chemokine axis does not account for enrichment of Foxp3(+) CD4(+) T cells in carcinogen-induced fibrosarcomas.Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation T cells and adoptive immunotherapy: recent developments and future prospects in gastrointestinal oncology.A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.Suppression of tumour-specific CD4⁺ T cells by regulatory T cells is associated with progression of human colorectal cancer Immunotherapy of Metastatic Colorectal Cancer: Prevailing Challenges and New Perspectives.Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determinated by multiparametric single cell mass cytometry analysis.Prognostic value of innate and adaptive immunity in colorectal cancer.The impact of regulatory T cells on carcinogen-induced sarcogenesis Tumor-released survivin induces a type-2 t cell response and decreases cytotoxic T cell function, in vitro.Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer.Tumor-infiltrating immune cells: triggers for tumor capsule disruption and tumor progression?Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability Regulatory T cells and tumour immunity - observations in mice and men.Immune cells in colorectal cancer: prognostic relevance and therapeutic strategies.Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness.NF-κB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer Targeting cytochrome P450 CYP1B1 with a therapeutic cancer vaccine.Positive and negative influences of regulatory T cells on tumour immunity.Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma.

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CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.

http://www.wikidata.org/entity/Q33268298

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2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.

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CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.

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CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.

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CD4+CD25+FOXP3+ regulatory T c ...... tients with colorectal cancer.

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Andrea Plant

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Andrew J Godkin

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Brian I Rees

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Gareth J Betts

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Geraint T Williams

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Jared Torkington

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Kate L Wright

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Richard Harrop

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Sarah L Clarke

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Tariq M El-Shanawany

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P2860

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

Use of complete eluted peptide sequence data from HLA-DR and -DQ molecules to predict T cell epitopes, and the influence of the nonbinding terminal regions of ligands in epitope selection.

Effector memory T cells, early metastasis, and survival in colorectal cancer.

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

The expression of 5T4 antigen in colorectal and gastric carcinoma

Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats.

Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells.

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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6596259

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17205133

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colorectal cancer

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