about
Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunityCD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.Interleukin-6 is crucial for recall of influenza-specific memory CD4 T cellsProgression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cells via blood vessels and lymphatics.Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer.A distinct chemokine axis does not account for enrichment of Foxp3(+) CD4(+) T cells in carcinogen-induced fibrosarcomas.CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphomaMonitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry.Tracking the kinetics of intrahepatic immune responses by repeated fine needle aspiration of the liver.Complement: central to innate immunity and bridging to adaptive responses.Suppression of tumour-specific CD4⁺ T cells by regulatory T cells is associated with progression of human colorectal cancerHolding T cells in check--a new role for complement regulators?Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice.Regulatory T cells and tumour immunity - observations in mice and men.Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+ T-cell immunity.Positive and negative influences of regulatory T cells on tumour immunity.Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology.Highly prevalent colorectal cancer-infiltrating LAP⁺ Foxp3⁻ T cells exhibit more potent immunosuppressive activity than Foxp3⁺ regulatory T cells.The paradox of NKp46+ natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon α treatment.Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.T cell subsets and colorectal cancer: discerning the good from the bad.Rapid innate control of antigen abrogates adaptive immunity.Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity.Antigen specificity determines the pro- or antitumoral nature of CD8+ T cells.Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity.Hunting for clues: Regulatory T cells and colorectal cancer.T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T-cell depletion.Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells.The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4⁺ and CD8⁺ T-cell immunity.Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors.Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4⁺ T-cell repertoire selectionThe MHC E locus in macaques is polymorphic and is conserved between macaques and humans.Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection.Home sweet home: the tumor microenvironment as a haven for regulatory T cells.CD59 blockade enhances antigen-specific CD4+ T cell responses in humans: a new target for cancer immunotherapy?Flow cytometry makes all the difference.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Awen Gallimore
@ast
Awen Gallimore
@en
Awen Gallimore
@es
Awen Gallimore
@nl
Awen Gallimore
@sl
type
label
Awen Gallimore
@ast
Awen Gallimore
@en
Awen Gallimore
@es
Awen Gallimore
@nl
Awen Gallimore
@sl
prefLabel
Awen Gallimore
@ast
Awen Gallimore
@en
Awen Gallimore
@es
Awen Gallimore
@nl
Awen Gallimore
@sl
P106
P1153
7005402663
P31
P496
0000-0001-6675-7004