A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. - Wikidata - wikimedia - TriplyDB

A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

http://www.wikidata.org/entity/Q33271900

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Modulation of cell cycle control during oocyte-to-embryo transitions The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation Molecular changes during egg activation.Mouse Emi2 as a distinctive regulatory hub in second meiotic metaphase Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability α-endosulfine (ENSA) regulates exit from prophase I arrest in mouse oocytes Regulation of APC/C activators in mitosis and meiosis.Female infertility in PDE3A(-/-) mice: polo-like kinase 1 (Plk1) may be a target of protein kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A(-/-) mice Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.Dimethyl sulfoxide inhibits spontaneous oocyte fragmentation and delays inactivation of maturation promoting factor (MPF) during the prolonged culture of ovulated murine oocytes in vitro.Mos in the oocyte: how to use MAPK independently of growth factors and transcription to control meiotic divisions.Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition.Punctuated cyclin synthesis drives early embryonic cell cycle oscillations.Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A.PP2A as a mercenary for warring kinases in the egg.Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition Shugoshin1 may play important roles in separation of homologous chromosomes and sister chromatids during mouse oocyte meiosis Second meiotic arrest and exit in frogs and mice.The M phase kinase Greatwall (Gwl) promotes inactivation of PP2A/B55delta, a phosphatase directed against CDK phosphosites.Features of programmed cell death in intact Xenopus oocytes and early embryos revealed by near-infrared fluorescence and real-time monitoring.Rat eggs cannot wait: Spontaneous exit from meiotic metaphase-II arrest.Vertebrate Reproduction.Regulation of Cell Division.Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail.PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation.Regulation of the action of early mitotic inhibitor 1 on the anaphase-promoting complex/cyclosome by cyclin-dependent kinases.Emi2-mediated inhibition of E2-substrate ubiquitin transfer by the anaphase-promoting complex/cyclosome through a D-box-independent mechanism.Non-proteolytic ubiquitylation counteracts the APC/C-inhibitory function of XErp1 The APC/C inhibitor XErp1/Emi2 is essential for Xenopus early embryonic divisions.

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A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

http://www.wikidata.org/entity/Q33271900

description

2007 nî lūn-bûn

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2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2007 թվականի փետրվարին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

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A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

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type

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A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

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A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

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A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

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A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest.

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J.CUB.2006.12.045

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Current Biology

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A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest

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Ayumi Yamada

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Christopher D Freel

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Hiroyuki Yamano

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Jeffrey J Tung

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Jennifer A Perry

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Maki Asano

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Michael Z Wang

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Qiju Wu

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Sally Kornbluth

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P2860

Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit.

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

Emi1 is required for cytostatic factor arrest in vertebrate eggs

Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family

Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

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