An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.
about
Systematically differentiating functions for alternatively spliced isoforms through integrating RNA-seq dataNovel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse StrainFunctional Brachyury binding sites establish a temporal read-out of gene expression in the Ciona notochordFibronectin contributes to notochord intercalation in the invertebrate chordate, Ciona intestinalisA novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biology'The chicken or the egg?' dilemma strikes back for the controlling mechanism in chordoma(#).From notochord formation to hereditary chordoma: the many roles of Brachyury.Converging paths to progress for skull base chordoma: Review of current therapy and future molecular targets.Molecular and clinical risk factors for recurrence of skull base chordomas: gain on chromosome 2p, expression of brachyury, and lack of irradiation negatively correlate with patient prognosis.Tissue microarray immunohistochemical detection of brachyury is not a prognostic indicator in chordomaThe brachyury Gly177Asp SNP is not associated with a risk of skull base chordoma in the Chinese population.Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies.Molecular pathology of bone tumours: diagnostic implications.The FGFR/MEK/ERK/brachyury pathway is critical for chordoma cell growth and survival.Molecular profiling of chordoma.FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation.[Novel molecular aspects of chordomas].Investigating microenvironmental regulation of human chordoma cell behaviourNovel targeted therapies in chordoma: an update.Overexpression of the BMP4/SMAD signaling pathway in skull base chordomas is associated with poor prognosis.The molecular aspects of chordoma.EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.Enhanced killing of chordoma cells by antibody-dependent cell-mediated cytotoxicity employing the novel anti-PD-L1 antibody avelumab.miR-219-5p inhibits proliferation and clonogenicity in chordoma cells and is associated with tumor recurrenceGenetic aberrations and molecular biology of skull base chordoma and chondrosarcoma.Validation of reference genes in human chordoma.Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathwayDefining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meetingBrachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells.Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer.The notochord: structure and functions.Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer.The driver landscape of sporadic chordomaChordoma: The Quest for Better Treatment Options.[Notochordal tumors : Benign notochordal tumors and chordomas].
P2860
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P2860
An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
An integrated functional genom ...... by brachyury (T) in chordoma.
@ast
An integrated functional genom ...... by brachyury (T) in chordoma.
@en
An integrated functional genom ...... network directed by brachyury
@nl
type
label
An integrated functional genom ...... by brachyury (T) in chordoma.
@ast
An integrated functional genom ...... by brachyury (T) in chordoma.
@en
An integrated functional genom ...... network directed by brachyury
@nl
prefLabel
An integrated functional genom ...... by brachyury (T) in chordoma.
@ast
An integrated functional genom ...... by brachyury (T) in chordoma.
@en
An integrated functional genom ...... network directed by brachyury
@nl
P2093
P2860
P50
P356
P1476
An integrated functional genom ...... by brachyury (T) in chordoma.
@en
P2093
Adrienne M Flanagan
Andrew C Nelson
Derek L Stemple
Dina Halai
Fitim Berisha
Nischalan Pillay
P2860
P304
P356
10.1002/PATH.4082
P577
2012-09-26T00:00:00Z