about
Threshold-controlled ubiquitination of the EGFR directs receptor fateTTP specifically regulates the internalization of the transferrin receptorThe eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathwayCrystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitinThe prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancerCell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval developmentLoss of negative regulation by Numb over Notch is relevant to human breast carcinogenesisEndocytic control of signaling at the plasma membraneThe Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells.Zebrafish numb and numblike are involved in primitive erythrocyte differentiationEps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.The alternative splicing factor Nova2 regulates vascular development and lumen formation.Molecular basis for the dual function of Eps8 on actin dynamics: bundling and cappingEps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)Alterations of the Notch pathway in lung cancer.Eps8 in the midst of GTPasesAbi1 is essential for the formation and activation of a WAVE2 signalling complexReciprocal repression between P53 and TCTPNUMB controls p53 tumour suppressor activityBiological and molecular heterogeneity of breast cancers correlates with their cancer stem cell contentRegulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complexSelective high-level expression of epsin 3 in gastric parietal cells, where it is localized at endocytic sites of apical canaliculiIncreased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamicsEps8 controls actin-based motility by capping the barbed ends of actin filamentsLoss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in miceIn silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure.Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesisThe Eps15 homology (EH) domain.
P50
Q24296784-934C5F15-F36D-4F83-8EE9-633C83B5CDDAQ24297900-0DB6A2A3-6176-4FE1-80E4-B50093FB43F9Q24298005-2F400FF4-91CF-4499-93D2-8612B3D95639Q24305560-CD1F3395-F380-4515-A079-76E013983B45Q24317638-30CB4668-2B3F-4633-AD39-7343644880F7Q24336986-AA6FC06A-3682-4102-95F2-998316389B5FQ24676117-0E534E4F-AE46-4DCB-B9AC-4925443E9AA7Q26766251-93DDEAD5-DC3E-4F6E-819C-097D9A9E4DCFQ27309278-7A5F8372-857F-4839-9F99-AEBBF0C63F4BQ27315869-F983DA6D-D653-4DB4-8608-1925F89785D2Q27321482-26171244-5587-4015-AB23-3F6F87362E0EQ27321847-4CF2B853-7E62-45D7-A312-B7A36BE1A6AEQ27324384-E21CEDA7-24A3-4B19-BD06-8329FA529AB3Q27330089-1098E5B2-AFE5-4272-AC16-5058FCF07076Q27851544-59C9E261-86A4-4683-929D-AB018A2EC309Q28215286-AEB0F3F2-99B2-4CDD-8A9F-F80920E3726CQ28253079-F1151161-C0B1-4F5A-88FF-E308CE73AEA1Q28255116-3937DECE-7843-4F91-96D5-C00DB1CE99F9Q28263413-8308D623-FCDD-4628-8F67-A0DFA76F7751Q28270471-E42391BD-9B2A-41C0-BBBA-8F677A3E1F88Q28504869-E5FDBDBB-CD0C-49F7-838F-2DA27AC22A90Q28505970-E9D8A33A-233E-43B1-A04E-122A312635E5Q28511738-A9855E07-122E-4F2D-BD88-2E3D55A55954Q28585492-DF25FE76-1A1D-4DE1-A28D-3466CBB6E303Q28593794-EE3970E3-D1FA-474C-93EE-ECB9655F1D92Q28748684-EE27B2A2-F1EA-42F3-AEA6-EA36CDBE2C69Q30332576-1796F5BF-B8FB-4874-A98E-D422E1A0AEDCQ30543591-DE058E53-9EF9-4E2B-A0ED-61D189057258Q30584664-C1626E54-C27B-4F51-B921-B6FA2C4CCE3CQ30652368-8D493537-C1C4-44F6-BA9F-F602B746652DQ30827834-5023D599-EC47-4472-9091-F828F03A32B6
P50
description
onderzoeker
@nl
name
Pier Paolo Di Fiore
@ast
Pier Paolo Di Fiore
@en
Pier Paolo Di Fiore
@nl
Pier Paolo Di Fiore
@sl
type
label
Pier Paolo Di Fiore
@ast
Pier Paolo Di Fiore
@en
Pier Paolo Di Fiore
@nl
Pier Paolo Di Fiore
@sl
prefLabel
Pier Paolo Di Fiore
@ast
Pier Paolo Di Fiore
@en
Pier Paolo Di Fiore
@nl
Pier Paolo Di Fiore
@sl
P106
P21
P31
P5463
Di_Fiore_Pier