Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.
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Sobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology ModelsDecision-tree based model analysis for efficient identification of parameter relations leading to different signaling statesLeveraging systems biology approaches in clinical pharmacologyPhenotypic evolutionary models in stem cell biology: replacement, quiescence, and variabilityA test of highly optimized tolerance reveals fragile cell-cycle mechanisms are molecular targets in clinical cancer trialsSBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool.Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic dataNarrative-based computational modelling of the Gp130/JAK/STAT signalling pathway.Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens.Modeling and analysis of the molecular basis of pain in sensory neurons.A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems.Tav4SB: integrating tools for analysis of kinetic models of biological systemsInferring robust gene networks from expression data by a sensitivity-based incremental evolution method.Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways.Computational modeling of mammalian signaling networks.Improving embryonic stem cell expansion through the combination of perfusion and Bioprocess model design.Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cellsCellular level models as tools for cytokine design.Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activationStem cell modeling: From gene networks to cell populations.Computational models of the JAK1/2-STAT1 signalingThe Role of the Leukemia Inhibitory Factor (LIF) - Pathway in Derivation and Maintenance of Murine Pluripotent Stem Cells.Progress and prospects for stem cell engineering.Cross-scale sensitivity analysis of a non-small cell lung cancer model: linking molecular signaling properties to cellular behaviorMicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance.A mechanistic pharmacodynamic model of IRAK-4 drug inhibition in the Toll-like receptor pathway.A magnetic cell-based sensor.Reducing experimental variability in variance-based sensitivity analysis of biochemical reaction systems.Parameter uncertainty quantification using surrogate models applied to a spatial model of yeast mating polarization.
P2860
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P2860
Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Sensitivity analysis of intrac ...... ts for stem cell fate control.
@ast
Sensitivity analysis of intrac ...... ts for stem cell fate control.
@en
type
label
Sensitivity analysis of intrac ...... ts for stem cell fate control.
@ast
Sensitivity analysis of intrac ...... ts for stem cell fate control.
@en
prefLabel
Sensitivity analysis of intrac ...... ts for stem cell fate control.
@ast
Sensitivity analysis of intrac ...... ts for stem cell fate control.
@en
P2093
P2860
P1476
Sensitivity analysis of intrac ...... ts for stem cell fate control.
@en
P2093
Alborz Mahdavi
Patrick Bhola
Peter W Zandstra
Ryan E Davey
P2860
P356
10.1371/JOURNAL.PCBI.0030130
P577
2007-07-01T00:00:00Z