Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes.
about
5'-UTR RNA G-quadruplexes: translation regulation and targetingRNA Secondary Structure Modulates FMRP's Bi-Functional Role in the MicroRNA PathwayThe biology of DHX9 and its potential as a therapeutic targetThe RNA helicase A in malignant transformationG-quadruplexes and helicasesReplication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stabilityDExD/H-box RNA helicases in ribosome biogenesisRNA helicase proteins as chaperones and remodelersG-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeMOV10 and FMRP regulate AGO2 association with microRNA recognition elementsDHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cellsSuppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.Dependence of p53-deficient cells on the DHX9 DExH-box helicase.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionInsights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase.RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1The Yin and Yang of R-loop biology.RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation.Translational repression of cyclin D3 by a stable G-quadruplex in its 5' UTR: implications for cell cycle regulationTumor cell survival dependence on the DHX9 DExH-box helicaseThe yin and yang of repair mechanisms in DNA structure-induced genetic instability.The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability.The tale of RNA G-quadruplex.Human Ribonuclease H1 resolves R loops and thereby enables progression of the DNA replication fork.R-loop: an emerging regulator of chromatin dynamics.RNA G-quadruplexes and their potential regulatory roles in translation.Replication Fork Protection Factors Controlling R-Loop Bypass and SuppressionTranslational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region.Human DDX21 binds and unwinds RNA guanine quadruplexes.QGRS-H Predictor: a web server for predicting homologous quadruplex forming G-rich sequence motifs in nucleotide sequences.Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.RNA G-Quadruplexes as Key Motifs of the Transcriptome.Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism.The RNA helicase DHX9 establishes nucleolar heterochromatin, and this activity is required for embryonic stem cell differentiation.The G-quadruplex (G4) resolvase DHX36 efficiently and specifically disrupts DNA G4s via a translocation-based helicase mechanism.Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair.SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability.RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.
P2860
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P2860
Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Human DHX9 helicase preferenti ...... (R-loops) and G-quadruplexes.
@ast
Human DHX9 helicase preferenti ...... (R-loops) and G-quadruplexes.
@en
type
label
Human DHX9 helicase preferenti ...... (R-loops) and G-quadruplexes.
@ast
Human DHX9 helicase preferenti ...... (R-loops) and G-quadruplexes.
@en
prefLabel
Human DHX9 helicase preferenti ...... (R-loops) and G-quadruplexes.
@ast
Human DHX9 helicase preferenti ...... (R-loops) and G-quadruplexes.
@en
P1433
P1476
Human DHX9 helicase preferenti ...... (R-loops) and G-quadruplexes.
@en
P2093
Frank Grosse
Prasun Chakraborty
P304
P356
10.1016/J.DNAREP.2011.04.013
P577
2011-05-10T00:00:00Z