Direct measurement of a pK(a) near neutrality for the catalytic cytosine in the genomic HDV ribozyme using Raman crystallography. - Wikidata - wikimedia - TriplyDB

Direct measurement of a pK(a) near neutrality for the catalytic cytosine in the genomic HDV ribozyme using Raman crystallography.

Direct measurement of a pK(a) near neutrality for the catalytic cytosine in the genomic HDV ribozyme using Raman crystallography.

http://www.wikidata.org/entity/Q33302034

about

Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme Identification of an Imino Group Indispensable for Cleavage by a Small Ribozyme The structural basis of RNA-catalyzed RNA polymerization.A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain Chemistry and Biology of Self-Cleaving Ribozymes A Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme Activation Quantum mechanical/molecular mechanical free energy simulations of the self-cleavage reaction in the hepatitis delta virus ribozyme.Intrinsic acid-base properties of a hexa-2'-deoxynucleoside pentaphosphate, d(ApGpGpCpCpT): neighboring effects and isomeric equilibria.Disparate HDV ribozyme crystal structures represent intermediates on a rugged free-energy landscape.The role of an active site Mg(2+) in HDV ribozyme self-cleavage: insights from QM/MM calculations.Role of tautomerism in RNA biochemistry.The pH dependence of hairpin ribozyme catalysis reflects ionization of an active site adenine Base ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world.The glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphate Characterization of the Structure and Dynamics of the HDV Ribozyme at Different Stages Along the Reaction Path.Constant pH Molecular Dynamics Simulations of Nucleic Acids in Explicit Solvent.Assessment of metal-assisted nucleophile activation in the hepatitis delta virus ribozyme from molecular simulation and 3D-RISM.Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.Multiscale methods for computational RNA enzymology.Transition State Features in the Hepatitis Delta Virus Ribozyme Reaction Revealed by Atomic Perturbations.pH-dependent dynamics of complex RNA macromolecules Towards Accurate Prediction of Protonation Equilibrium of Nucleic Acids.Secondary structure confirmation and localization of Mg2+ ions in the mammalian CPEB3 ribozyme.Molecular dynamics suggest multifunctionality of an adenine imino group in acid-base catalysis of the hairpin ribozyme.Rapid and simple ribozymic aminoacylation using three conserved nucleotides.Raman crystallography of RNA.Two distinct catalytic strategies in the hepatitis δ virus ribozyme cleavage reaction.The DNA and RNA sugar-phosphate backbone emerges as the key player. An overview of quantum-chemical, structural biology and simulation studies.Nucleic acid catalysis: metals, nucleobases, and other cofactors.Properties and reactivity of nucleic acids relevant to epigenomics, transcriptomics, and therapeutics.Charged nucleobases and their potential for RNA catalysis.Experimental approaches for measuring pKa's in RNA and DNA.Quantum Mechanical/Molecular Mechanical Study of the HDV Ribozyme: Impact of the Catalytic Metal Ion on the Mechanism.Inverse thio effects in the hepatitis delta virus ribozyme reveal that the reaction pathway is controlled by metal ion charge density.A catalytic metal ion interacts with the cleavage Site G.U wobble in the HDV ribozyme.Metal binding motif in the active site of the HDV ribozyme binds divalent and monovalent ions.Competition between Co(NH(3)(6)3+ and inner sphere Mg2+ ions in the HDV ribozyme.Identification of the catalytic Mg²⁺ ion in the hepatitis delta virus ribozyme.Thio effects and an unconventional metal ion rescue in the genomic hepatitis delta virus ribozyme.

P2860

Q27651015-3187BDCD-3EE4-4DCE-ABB0-7045945613A1 Q27654589-2C5027A1-C3D8-461E-BD3A-F0FB279B5BE1 Q27671854-B4465834-BF5F-4192-BE61-5C7B909877F2 Q27673382-D230793E-06C1-48D4-BCDC-EC459F5400C6 Q27689573-EF79B517-15F0-42F4-A286-D54737609E0D Q28087730-FA9D6AC6-182E-489E-83A9-E76DD2BE52E8 Q28821468-2B67707A-1429-4428-9D00-4349F4FFADF8 Q30574062-69421B7F-41A1-4762-82E9-3FED74812073 Q30617998-C9A9F989-4928-44B0-8C55-DBF07B5CAC2D Q33967967-0DE9A5EB-70D2-4626-8A3B-4F7DA500127C Q34633103-DFA0A250-B4DE-4248-BF9F-04922B76CB06 Q34761573-3B49F006-1FA6-4C6F-813F-DA4F9E1A17FA Q34978942-3C621503-1E68-49BE-962D-9E0EE7EE109C Q35038177-20B48BEA-F3CB-49B8-94C8-7AE1FD6E25AC Q35217480-F64D8750-6338-4461-839C-0EB7BA7D23D2 Q35628399-380B0BB2-2BB8-48E9-8511-26819C18E216 Q35751959-38B82E89-8907-4C80-9251-E0CA39190240 Q35952771-5F3EAD09-9A23-4EA9-BAEB-097EAE474B08 Q36455539-9C944147-064E-4DC1-8295-A34C09C63BCB Q36540017-B2A5B1F2-6459-47B6-B631-4FA958DFB114 Q36592176-4A712F3D-B0B7-47C8-9016-DF86974E6A32 Q36697118-DDA4536C-0D31-4129-95CE-C2B4FC008CB3 Q36697198-43BAD579-E581-4A8D-BAA3-0C5FD648C2C4 Q36812728-02CBD91C-E65B-4A4A-B6F5-E70DFC2B100E Q37142097-1C3EC316-9B54-4535-9D3A-7E48723F5F2D Q37360129-7B1D3A2A-35CA-46A0-8D58-141456353DC9 Q37366827-A6C396C6-F6AC-4C43-9ADB-CFEC6B154E09 Q37946428-BA4F58B5-0FC9-4726-8C1E-3B23366D90E7 Q38052698-2AB88448-F24D-476E-80DA-C726EB65356C Q38204496-FAD511E5-57DD-4B9D-B889-A6CA23E173C0 Q38780402-4F8207D0-0EDC-4EF4-8F2A-B6674DF559DA Q38985909-AEA64DEA-FE0D-42CC-87F4-DC957734FE4F Q39093016-986CB8EC-75E0-4069-9EA6-BA24EE25C547 Q39669410-57C37655-4756-411F-872F-CB8FE620144B Q39959277-9CAA083B-D478-421C-A4D7-7FB7BD8606D2 Q41845041-04AE2178-E676-4BE0-BCAA-B9DDDB9252DC Q42040369-4EEB3CF9-FBB3-495E-AC62-5C0F42639C51 Q42078666-9E1B726A-8CCE-434D-81AB-C45F05F7526D Q42193020-AD06FBD9-65D8-49E9-8649-6E54426C49A0 Q42272436-D6397775-FC25-48B2-95A5-DEC307C72777

P2860

Direct measurement of a pK(a) near neutrality for the catalytic cytosine in the genomic HDV ribozyme using Raman crystallography.

http://www.wikidata.org/entity/Q33302034

description

2007 nî lūn-bûn

@nan

2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Direct measurement of a pK

@nl

Direct measurement of a pK(a) ...... e using Raman crystallography.

@ast

Direct measurement of a pK(a) ...... e using Raman crystallography.

@en

type

label

Direct measurement of a pK

@nl

Direct measurement of a pK(a) ...... e using Raman crystallography.

@ast

Direct measurement of a pK(a) ...... e using Raman crystallography.

@en

prefLabel

Direct measurement of a pK

@nl

Direct measurement of a pK(a) ...... e using Raman crystallography.

@ast

Direct measurement of a pK(a) ...... e using Raman crystallography.

@en

P1433

Q33302034-9C11C61B-C63E-4A70-A7EC-2E8942ECCC3C

P1476

Q33302034-8792E1DB-6789-4C9B-AC10-069ADDBEC2CD

P2093

Q33302034-08A53C21-8931-46D7-BDEE-3BAE18002DEE

Q33302034-10F16F65-AAE8-438B-B88D-2D5147EA9E77

Q33302034-5509D699-F7AB-4281-AC47-FDE542A0A4C1

Q33302034-6318BF79-8A9F-47AF-BB99-F04B06B20933

Q33302034-66469C97-E75C-4C46-9619-7DCC45B4ED7D

Q33302034-75E9697A-EF8F-46C2-A775-964A97A445F4

Q33302034-78370F14-65A2-451A-A9E5-0BC7885D49D2

P304

Q33302034-EB274D03-E1E8-4A62-B4D9-CB2AD9CCCB9F

P31

Q33302034-9ED9C09E-CAAC-4977-87DE-2B2ED2235374

P356

Q33302034-CF11B10E-AF16-40CD-BD88-11E9955628FF

P407

Q33302034-6B91B956-638B-4D6A-B9D5-C91A993AE698

P433

Q33302034-0B9E1C4B-310E-44BD-93A1-655BF4C65ADE

P478

Q33302034-C33BF1F7-B88D-4EC7-ACDB-24806F9B38AC

P50

Q33302034-ADA97414-B3F2-4D2B-BD84-DD93E0E63A6E

P577

Q33302034-E004B7CF-0F2F-4158-BD95-AD95687743CB

P5875

Q33302034-BCC8FF97-F94B-4603-B532-1C6693A1882F

P698

Q33302034-46C169FE-7F5B-4EC9-8AC5-D69291553B24

P921

Q33302034-C265A2C6-8E95-4CCA-940C-EB198F7EA319

P356

P1433

Journal of the American Chemical Society

P1476

Direct measurement of a pK(a) ...... e using Raman crystallography.

@en

P2093

Bo Gong

http://www.w3.org/2001/XMLSchema#string

Durga M Chadalavada

http://www.w3.org/2001/XMLSchema#string

Elaine Chase

http://www.w3.org/2001/XMLSchema#string

Jui-Hui Chen

http://www.w3.org/2001/XMLSchema#string

Paul R Carey

http://www.w3.org/2001/XMLSchema#string

Philip C Bevilacqua

http://www.w3.org/2001/XMLSchema#string

Rieko Yajima

http://www.w3.org/2001/XMLSchema#string

P304

13335-13342

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/JA0743893

http://www.w3.org/2001/XMLSchema#string

P407

P433

43

http://www.w3.org/2001/XMLSchema#string

P478

129

http://www.w3.org/2001/XMLSchema#string

P50

Barbara L. Golden

P577

2007-10-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5919729

http://www.w3.org/2001/XMLSchema#string

P698

17924627

http://www.w3.org/2001/XMLSchema#string

P921