HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling.
about
The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbingSubversion of the actin cytoskeleton during viral infectionHow HIV takes advantage of the cytoskeleton in entry and replicationHIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenonSingle-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functionsHeterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 NefHIV-1 Nef: a multifaceted modulator of T cell receptor signaling.Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC.Nef inhibits glucose uptake in adipocytes and contributes to insulin resistance in human immunodeficiency virus type I infection.A Conserved GPG-Motif in the HIV-1 Nef Core Is Required for Principal Nef-Activities.Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cellsEngagement of the CD4 receptor affects the redistribution of Lck to the immunological synapse in primary T cells: implications for T-cell activation during human immunodeficiency virus type 1 infection.Mechanisms of HIV-1 Nef function and intracellular signaling.HIV-1 at the immunological and T-lymphocytic virological synapse.The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms.The adaptor protein SLP-76 regulates HIV-1 release and cell-to-cell transmission in T cells.HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse.Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.Rho'ing in and out of cells: viral interactions with Rho GTPase signalingMicroglia-derived HIV Nef+ exosome impairment of the blood-brain barrier is treatable by nanomedicine-based delivery of Nef peptides.Murid Gammaherpesvirus Latency-Associated Protein M2 Promotes the Formation of Conjugates between Transformed B Lymphoma Cells and T Helper Cells.HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.HIV-1 Nef and T-cell activation: a history of contradictions.Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation.Modulation of HIV pathogenesis and T-cell signaling by HIV-1 NefNef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase.Inhibition of T-cell receptor-induced actin remodeling and relocalization of Lck are evolutionarily conserved activities of lentiviral Nef proteins.HIV-1 Nef disrupts membrane-microdomain-associated anterograde transport for plasma membrane delivery of selected Src family kinases.Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef functionIL-23 signaling in Th17 cells is inhibited by HIV infection and is not restored by HAART: Implications for persistent immune activation.All-Round Manipulation of the Actin Cytoskeleton by HIV.Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef.SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue
P2860
Q24322829-57515397-BDB1-4E14-804D-0205A1E80037Q24633026-5C3FE84E-FB8B-4C52-A0CF-D565EF3D974CQ27021639-02B4F598-A681-4917-8430-95E49A087ED6Q30009553-F0CD576A-78CF-47AD-91CC-16A94F20A1D3Q30010165-8846B2DF-B6A3-4D91-B878-D15E56B8A3FDQ33619431-6DEE5E47-7CAD-451F-AF86-31FEA8555F66Q34316824-75CBF802-7EF3-4FD9-B1D5-A83FEF34A0B1Q34531834-1FD9FF03-A2BB-408E-9B25-EFCA1A85416EQ35000876-5A01EBF4-7377-421F-B798-5F9F813CD78EQ35877701-B24554DD-29F8-4008-B082-6B99DA0C489BQ36143620-E5DFA824-DFAC-48FB-96C9-7C568A113B96Q36937131-E9FA4848-27BB-4C9E-9A28-60FF414D7C0DQ37051575-1DB68322-CE58-44C7-B88C-6F83C0434BA5Q37183848-D1751328-B1C4-4071-A457-245531B2ABCBQ37247063-8A37AB3B-631C-4DF1-A324-27E787A61C22Q37415400-577BCDBD-86A3-4516-AA32-025812E9635DQ37532593-AC4E7A87-55E5-4A0D-A5BA-A05DDB13E585Q37537767-5B8E2C19-70A6-4D6B-86EB-B1568D3D20C2Q37796606-92FAB702-445B-41BB-9DF5-5116440240FBQ38151848-0D04EEF3-F153-411D-BA71-112F4BB93399Q38201237-62A0DC89-0713-4E93-BD47-54A10D5334E4Q38814829-D23CA2B1-7A3A-41EF-A624-204322F2C7C2Q38821524-9518E62B-4104-4A71-B90A-E97B4A0D2DF8Q38951336-68EDDCE6-EA41-41D4-92BD-E56DE9F42F2EQ39321661-B4741F8D-B626-446D-9F1B-9C560EF36E11Q39358737-8B90CEAC-018D-4495-AAE5-5E48A76A9DDAQ39577894-8EDB5DBF-EB45-4BC5-8B8B-DD1EA244DF00Q39852042-53CCEB38-AB59-4D1D-AE05-24458CCBCC02Q41888042-20486BFB-A7DC-4BE2-9520-DCFC5222D65EQ42265942-DFE74516-5F22-4DF2-A9D8-A9749B4D6FC4Q42413312-EE17F5A7-279B-4F9B-BD49-956B06305728Q45406195-12D1BEAE-8D01-4F32-9A0D-99A37378833CQ48104489-DB17B628-9102-4B1E-99B3-F4C7B30B87BDQ51733716-F226B21A-A23E-4415-B073-0EAFD6D5D108Q58734354-31C85F6A-FD5D-4267-8073-C266B527FFA0
P2860
HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling.
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@ast
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@en
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@nl
type
label
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@ast
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@en
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@nl
prefLabel
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@ast
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@en
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@nl
P2860
P1433
P1476
HIV-1 Nef employs two distinct ...... TCR induced actin remodeling.
@en
P2093
Claudia Haller
Susanne Rauch
P2860
P356
10.1371/JOURNAL.PONE.0001212
P407
P577
2007-11-21T00:00:00Z