Role of the ubiquitin proteasome system in Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Role of the ubiquitin proteasome system in Alzheimer's disease.

Role of the ubiquitin proteasome system in Alzheimer's disease.

http://www.wikidata.org/entity/Q33307872

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Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation A novel neuron-enriched protein SDIM1 is down regulated in Alzheimer's brains and attenuates cell death induced by DNAJB4 over-expression in neuro-progenitor cells Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes Protein phosphatases and Alzheimer's disease The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer's Disease and Spinal Cord Injury iTRAQ analysis of complex proteome alterations in 3xTgAD Alzheimer's mice: understanding the interface between physiology and disease Neuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development The ubiquitin system, disease, and drug discovery.Viable mouse gene ablations that robustly alter brain Aβ levels are rare.A molecular hypothesis to explain direct and inverse co-morbidities between Alzheimer's Disease, Glioblastoma and Lung cancer The ubiquitin-proteasome pathway and synaptic plasticity.Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease.Curcumin prevents formation of polyglutamine aggregates by inhibiting Vps36, a component of the ESCRT-II complex.Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration.Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks.CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase.Identification of Differentially Expressed Genes through Integrated Study of Alzheimer's Disease Affected Brain Regions Coordination between proteasome impairment and caspase activation leading to TAU pathology: neuroprotection by cAMP.Label-free quantitative LC-MS proteomics of Alzheimer's disease and normally aged human brains.PathNet: a tool for pathway analysis using topological information Molecular events linking cholesterol to Alzheimer's disease and inclusion body myositis in a rabbit model.Brain site-specific proteome changes in aging-related dementia.18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures.Genetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction.The role and therapeutic targeting of α-, β- and γ-secretase in Alzheimer's disease Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease.Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans Protein Quality Control by Molecular Chaperones in Neurodegeneration.Proteomics moves from expression to turnover: update and future perspective.Review: unchained maladie - a reassessment of the role of Ubb(+1) -capped polyubiquitin chains in Alzheimer's disease.Neuronal ubiquitin homeostasis The proteasome function reporter GFPu accumulates in young brains of the APPswe/PS1dE9 Alzheimer's disease mouse model.Oxidative Stress and Protein Quality Control Systems in the Aged Canine Brain as a Model for Human Neurodegenerative Disorders.The mechanisms of Mallory-Denk body formation are similar to the formation of aggresomes in Alzheimer's disease and other neurodegenerative disorders.Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases.UPS Activation in the Battle Against Aging and Aggregation-Related Diseases: An Extended Review.Proteolysis, synaptic plasticity and memory.

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Role of the ubiquitin proteasome system in Alzheimer's disease.

http://www.wikidata.org/entity/Q33307872

description

2007 nî lūn-bûn

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2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Role of the ubiquitin proteasome system in Alzheimer's disease.

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Role of the ubiquitin proteasome system in Alzheimer's disease.

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Role of the ubiquitin proteasome system in Alzheimer's disease.

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type

label

Role of the ubiquitin proteasome system in Alzheimer's disease.

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Role of the ubiquitin proteasome system in Alzheimer's disease.

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Role of the ubiquitin proteasome system in Alzheimer's disease.

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prefLabel

Role of the ubiquitin proteasome system in Alzheimer's disease.

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Role of the ubiquitin proteasome system in Alzheimer's disease.

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Role of the ubiquitin proteasome system in Alzheimer's disease.

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1471-2091-8-S1-S12

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BMC Biochemistry

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Role of the ubiquitin proteasome system in Alzheimer's disease.

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Ashok N Hegde

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Sudarshan C Upadhya

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Creative Commons Attribution 2.0 Generic

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

Amyloid plaque core protein in Alzheimer disease and Down syndrome

Pathways towards and away from Alzheimer's disease

Neuropathological stageing of Alzheimer-related changes

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Alzheimer's disease: genes, proteins, and therapy

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

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8 Suppl 1

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Alzheimer's disease

ubiquitin-proteasome system

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