Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia. - Wikidata - wikimedia - TriplyDB

Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia.

Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia.

http://www.wikidata.org/entity/Q33310158

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Telomere biology: Rationale for diagnostics and therapeutics in cancer Identifying High-Risk Chronic Lymphocytic Leukemia: A Pathogenesis-Oriented Appraisal of Prognostic and Predictive Factors in Patients Treated with Chemotherapy with or without Immunotherapy Hypermutation in human cancer genomes: footprints and mechanisms Telomerase contributes to fludarabine resistance in primary human leukemic lymphocytes.Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility.Increased genomic alteration complexity and telomere shortening in B-CLL cells resistant to radiation-induced apoptosis.Dysregulation of H/ACA ribonucleoprotein components in chronic lymphocytic leukemia.HTLV-1 positive and negative T cells cloned from infected individuals display telomerase and telomere genes deregulation that predominate in activated but untransformed CD4+ T cells.Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.Altered mRNA expression of telomere-associated genes in monoclonal gammopathy of undetermined significance and multiple myeloma.Dyskerin overexpression in human hepatocellular carcinoma is associated with advanced clinical stage and poor patient prognosis Telomere profiling: toward glioblastoma personalized medicine.The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia.Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes.Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders.Shelterin dysfunction and p16(INK4a)-mediated growth inhibition in HIV-1-specific CD8 T cells.Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.Telomere status in chronic lymphocytic leukemia with TP53 disruption.ERCC1 and telomere status in breast tumours treated with neoadjuvant chemotherapy and their association with patient prognosis Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks.Detection of chromothripsis-like patterns with a custom array platform for chronic lymphocytic leukemia.The shelterin complex and hematopoiesis.Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis.A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment.Chromatin redistribution of the DEK oncoprotein represses hTERT transcription in leukemias Dynamics of telomeric chromatin at the crossroads of aging and cancer.Telomere dysfunction and its role in haematological cancer.Telomeric impact of conventional chemotherapy.The genomic landscape of chronic lymphocytic leukaemia: biological and clinical implications.Treating Cancer by Targeting Telomeres and Telomerase.Mechanisms and clinical applications of chromosomal instability in lymphoid malignancy.Aberrant levels of SUV39H1 and SUV39H2 methyltransferase are associated with genomic instability in chronic lymphocytic leukemia.Androgen receptor interacts with telomeric proteins in prostate cancer cells.DKC1 overexpression associated with prostate cancer progression.T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.Transcriptional activation of hTERT, the human telomerase reverse transcriptase, by nuclear factor of activated T cells.Differential senescence capacities in meibomian gland carcinoma and basal cell carcinoma.Correlation of dyskerin expression with active proliferation independent of telomerase.

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Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia.

http://www.wikidata.org/entity/Q33310158

description

2007 nî lūn-bûn

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2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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Changes in the expression of t ...... -chronic lymphocytic leukemia.

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Aude Roborel de Climens

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Aurélie Belleville

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Claire t'kint de Roodenbeke

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Delphine Poncet

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Eric Gilson

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Evelyne Callet-Bauchu

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Gilles Salles

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Hélène Merle-Beral

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Jozo Delic

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2388-2391

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5770379

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