Characterization of chemical libraries for luciferase inhibitory activity.
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Identification of Novel Inhibitors of the Type I Interferon Induction Pathway Using Cell-Based High-Throughput ScreeningMolecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a ReporterTitration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase InhibitorsThe ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domainProfile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assaysMethod for Assaying the Lipid Kinase Phosphatidylinositol-5-phosphate 4-kinase α in Quantitative High-Throughput Screening (qHTS) Bioluminescent FormatA coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases.A specific mechanism for nonspecific activation in reporter-gene assaysA robotic platform for quantitative high-throughput screeningA basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolutionThe cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase.Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay.The pilot phase of the NIH Chemical Genomics Center.A novel method for mining highly imbalanced high-throughput screening data in PubChem.Comparison of bioluminescent kinase assays using substrate depletion and product formation.A high-throughput 1,536-well luminescence assay for glutathione S-transferase activity.Apparent activity in high-throughput screening: origins of compound-dependent assay interferenceBioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets.Evaluation of a luciferase-based reporter assay as a screen for inhibitors of estrogen-ERα-induced proliferation of breast cancer cells.Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biologyAnalysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activityA chemical screen identifies small molecules that regulate hepcidin expression.The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform.Studies of dynamic protein-protein interactions in bacteria using Renilla luciferase complementation are undermined by nonspecific enzyme inhibitionThe essential roles of chemistry in high-throughput screening triagePAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.High-throughput screening identifies aclacinomycin as a radiosensitizer of EGFR-mutant non-small cell lung cancerIdentification of a new class of small molecules that efficiently reactivate latent Epstein-Barr Virus.The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomicsA novel aromatic carboxylic acid inactivates luciferase by acylation of an enzymatically active regulatory lysine residue.Microcontroller-assisted compensation of adenosine triphosphate levels: instrument and method development.PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2.Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase.A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation.Selecting, Acquiring, and Using Small Molecule Libraries for High-Throughput Screening.High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.Avoiding Fluorescence Assay Interference-The Case for Diaphorase.
P2860
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P2860
Characterization of chemical libraries for luciferase inhibitory activity.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Characterization of chemical libraries for luciferase inhibitory activity.
@ast
Characterization of chemical libraries for luciferase inhibitory activity.
@en
Characterization of chemical libraries for luciferase inhibitory activity.
@nl
type
label
Characterization of chemical libraries for luciferase inhibitory activity.
@ast
Characterization of chemical libraries for luciferase inhibitory activity.
@en
Characterization of chemical libraries for luciferase inhibitory activity.
@nl
prefLabel
Characterization of chemical libraries for luciferase inhibitory activity.
@ast
Characterization of chemical libraries for luciferase inhibitory activity.
@en
Characterization of chemical libraries for luciferase inhibitory activity.
@nl
P2093
P50
P356
P1476
Characterization of chemical libraries for luciferase inhibitory activity.
@en
P2093
David J Diller
Douglas S Auld
James Inglese
Ronald L Johnson
P304
P356
10.1021/JM701302V
P407
P577
2008-03-26T00:00:00Z