Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility. - Wikidata - wikimedia - TriplyDB

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.

http://www.wikidata.org/entity/Q33331556

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High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase An evolutionary perspective on the kinome of malaria parasites Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis Using genetic methods to define the targets of compounds with antimalarial activity The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion.A cyclic GMP signalling module that regulates gliding motility in a malaria parasite An essential malaria protein defines the architecture of blood-stage and transmission-stage parasites.TgCDPK3 regulates calcium-dependent egress of Toxoplasma gondii from host cells Regulation of the Plasmodium Motor Complex: PHOSPHORYLATION OF MYOSIN A TAIL-INTERACTING PROTEIN (MTIP) LOOSENS ITS GRIP ON MyoA The Cryptosporidium parvum Kinome Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes Effects of calcium signaling on Plasmodium falciparum erythrocyte invasion and post-translational modification of gliding-associated protein 45 (PfGAP45)Rab11A-controlled assembly of the inner membrane complex is required for completion of apicomplexan cytokinesis Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90 Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1 Dissection of mechanisms involved in the regulation of Plasmodium falciparum calcium-dependent protein kinase 4 A DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosis A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis Using small molecules to dissect mechanisms of microbial pathogenesis.The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony.Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence.Optimization of an imidazopyridazine series of inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.A research agenda for malaria eradication: basic science and enabling technologies Use of the kinase inhibitor analog 1NM-PP1 reveals a role for Toxoplasma gondii CDPK1 in the invasion step.PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum.Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum.Expanding the Antimalarial Drug Arsenal-Now, But How?Quantitative in vivo analyses reveal calcium-dependent phosphorylation sites and identifies a novel component of the Toxoplasma invasion motor complex How apicomplexan parasites move in and out of cells.Regulation of Plasmodium falciparum glideosome associated protein 45 (PfGAP45) phosphorylation Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin

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P2860

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.

http://www.wikidata.org/entity/Q33331556

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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name

Gene expression signatures and ...... lasmodium falciparum motility.

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Gene expression signatures and ...... lasmodium falciparum motility.

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Gene expression signatures and ...... lasmodium falciparum motility.

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type

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Gene expression signatures and ...... lasmodium falciparum motility.

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Gene expression signatures and ...... lasmodium falciparum motility.

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Gene expression signatures and ...... lasmodium falciparum motility.

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Gene expression signatures and ...... lasmodium falciparum motility.

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Gene expression signatures and ...... lasmodium falciparum motility.

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Gene expression signatures and ...... lasmodium falciparum motility.

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Nature Chemical Biology

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Gene expression signatures and ...... lasmodium falciparum motility.

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Advait Nagle

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Arnab Chatterjee

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Badry Bursulaya

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Carsten Andersen

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Case McNamara

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Daniel Mason

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David Plouffe

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Eric C Peters

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Felix Marr

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Jeffrey Harper

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347-356

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scholarly article

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10.1038/NCHEMBIO.87

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6

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4

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Elizabeth Winzeler

Ghislain Breton

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5398897

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Plasmodium falciparum