A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction.
about
Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein Subunit MutantsA P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal PathogenesisA point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamicsIdentification of influenza endonuclease inhibitors using a novel fluorescence polarization assay.Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptorsRegulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.Regulator of G-protein signaling-21 (RGS21) is an inhibitor of bitter gustatory signaling found in lingual and airway epithelia.G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifsGIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.Cullin3-BTB interface: a novel target for stapled peptidesFluorescence polarization assays in small molecule screening.Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR ValidationGroup II activators of G-protein signalling and proteins containing a G-protein regulatory motif.Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.Fluorescence polarization assays in high-throughput screening and drug discovery: a reviewA capture coupling method for the covalent immobilization of hexahistidine tagged proteins for surface plasmon resonance.A homogeneous method to measure nucleotide exchange by α-subunits of heterotrimeric G-proteins using fluorescence polarization.Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein.Fluorescence polarization assays to measure interactions between Gα subunits of heterotrimeric G proteins and regulatory motifs.
P2860
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P2860
A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A high throughput fluorescence ...... oco motif/G-alpha interaction.
@ast
A high throughput fluorescence ...... oco motif/G-alpha interaction.
@en
type
label
A high throughput fluorescence ...... oco motif/G-alpha interaction.
@ast
A high throughput fluorescence ...... oco motif/G-alpha interaction.
@en
prefLabel
A high throughput fluorescence ...... oco motif/G-alpha interaction.
@ast
A high throughput fluorescence ...... oco motif/G-alpha interaction.
@en
P2093
P2860
P50
P1476
A high throughput fluorescence ...... oco motif/G-alpha interaction.
@en
P2093
Adam J Kimple
Francis S Willard
Gordon C Ibeanu
James Inglese
Mark Hughes
Robin E Muller
P2860
P304
P356
10.2174/138620708784534770
P577
2008-06-01T00:00:00Z