A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia.
about
Animal models of hemophiliaGutless adenovirus: last-generation adenovirus for gene therapyHelper-dependent adenoviral gene therapy mediates long-term correction of the clotting defect in the canine hemophilia A model.Adenoviral Vectors for Hemophilia Gene TherapyLarge-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories.Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects.Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.Helper-dependent adenoviral vectors for liver-directed gene therapy.Protein replacement therapy and gene transfer in canine models of hemophilia A, hemophilia B, von willebrand disease, and factor VII deficiency.Lentiviral gene transfer into the dorsal root ganglion of adult rats.Liver gene therapy: advances and hurdles.Gene transfer for hemophilia: can therapeutic efficacy in large animals be safely translated to patients?Therapeutic short hairpin RNA expression in the liver: viral targets and vectors.Optimal haemophilia care versus the reality.Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastomaGene therapy for liver enzyme deficiencies: what have we learned from models for Crigler-Najjar and tyrosinemia?Cloning and Large-Scale Production of High-Capacity Adenoviral Vectors Based on the Human Adenovirus Type 5.Gene therapy with helper-dependent adenoviral vectors: lessons from studies in large animal models.A rapid protocol for construction and production of high-capacity adenoviral vectors.Ad 2.0: a novel recombineering platform for high-throughput generation of tailored adenoviruses.Use of a murine secreted alkaline phosphatase as a non-immunogenic reporter gene in mice.A Novel Adenoviral Hybrid-vector System Carrying a Plasmid Replicon for Safe and Efficient Cell and Gene Therapeutic Applications.Gene therapy for hemophilia B mice with scAAV8-LP1-hFIX.Advances in Overcoming Immune Responses following Hemophilia Gene Therapy.Coagulation Factor IX for Hemophilia B Therapy.Toward gene therapy for hemophilia A with novel adenoviral vectors: successes and limitations in canine models.Effects of genetic fusion of factor IX to albumin on in vivo clearance in mice and rabbits.
P2860
Q27012571-E8D22D28-6F59-4027-8776-E85B5DA5D463Q28277560-F3B51B31-83D8-4222-B449-A8B182ACC701Q33371228-335AADF5-9FAB-4E74-8A17-88FEB9801189Q33690648-E590F533-2156-421E-AB66-6B9CC7BA3573Q33691820-9A4C05BD-94B1-4B9C-A96D-9D964F9390D0Q33881920-3DD9DDAB-3F87-4DAC-ABFD-70425649BFDBQ34343757-CD5B391C-BE42-4270-AC5E-931ADEFA08C8Q34982825-24FFB6D4-EFD6-49F3-AE08-BDEA0C670CDAQ35006603-F084C41E-FAB0-47B1-A38C-A893A48BE17BQ35231284-BB88BB49-A082-4BD1-A2ED-F8197FF35C87Q35904443-D6B90D8E-7725-4E63-A176-4C5D8337159AQ36230845-FFBDFF6E-A36F-40B5-8133-7C03DB356A12Q36384459-BD992FC9-5D0B-44F9-B790-056C60058592Q36399847-2A9C7B97-67E3-430C-981D-D9F98028A799Q36811505-283094BD-DE0A-46F7-8602-66D5DA4497DEQ37346064-7FD63468-6866-494C-A2F7-F1ED330B443CQ38795239-3442049B-A113-419D-B180-409B4BDAAE4EQ39358889-9C151363-E07A-4EC9-A7EA-EF8E7829BF57Q39859960-915EE9FA-7812-4841-9F22-16EFF06FA08BQ40175603-96EFF04B-2C7B-4905-945B-526AC91CD941Q40498278-A031C8FF-E24A-440C-BC3B-5DFDE352532BQ40596293-5FE8EBE4-2A2D-4CFC-883C-C89F8D3FBDD2Q40814418-AFB9D743-9AF6-450F-B57F-7B19804AC971Q42209182-A327E760-F444-4342-A3F3-E96195C2C989Q42256024-987676D9-1C45-4E76-A7C9-AD7641226E3EQ45858373-1AE4BC7D-FCD8-4C85-9576-8510D8E9990BQ45876933-94C6C019-A707-403A-ABEE-0459D820D32F
P2860
A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A gene-deleted adenoviral vect ...... toxicity or thrombocytopenia.
@ast
A gene-deleted adenoviral vect ...... toxicity or thrombocytopenia.
@en
type
label
A gene-deleted adenoviral vect ...... toxicity or thrombocytopenia.
@ast
A gene-deleted adenoviral vect ...... toxicity or thrombocytopenia.
@en
prefLabel
A gene-deleted adenoviral vect ...... toxicity or thrombocytopenia.
@ast
A gene-deleted adenoviral vect ...... toxicity or thrombocytopenia.
@en
P2093
P921
P1433
P1476
A gene-deleted adenoviral vect ...... toxicity or thrombocytopenia.
@en
P2093
Aaron M Dillow
Anja Ehrhardt
Dwight A Bellinger
Mark A Kay
Timothy C Nichols
P304
P356
10.1182/BLOOD-2003-01-0314
P407
P577
2003-06-12T00:00:00Z