Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection
about
Origins of HIV and the AIDS pandemicIncreased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpzIntact type I Interferon production and IRF7 function in sooty mangabeysIn vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis.Positive selection of HIV host factors and the evolution of lentivirus genesCounteraction of HLA-C-mediated immune control of HIV-1 by Nef.Immune dysregulation in human immunodeficiency virus infection: know it, fix it, prevent it?Link between primate lentiviral coreceptor usage and Nef function.Genetic identity and biological phenotype of a transmitted/founder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeysSystems biology of natural simian immunodeficiency virus infectionsThe presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 are not always linked in primate lentivirusesMechanisms of HIV-associated lymphocyte apoptosis: 2010Autophagy and HIVLentiviral Nef proteins manipulate T cells in a subset-specific mannerTracking the Emergence of Host-Specific Simian Immunodeficiency Virus env and nef Populations Reveals nef Early Adaptation and Convergent Evolution in Brain of Naturally Progressing Rhesus Macaques.Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ T cell counts in viremic HIV-2 infectionDeterminants in HIV-1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivoConservation of Nef function across highly diverse lineages of SIVsmm.Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophagesThe inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses.Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys.Downregulation of the T-cell receptor by human immunodeficiency virus type 2 Nef does not protect against disease progression.Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functionsPrimate Lentiviruses Modulate NF-κB Activity by Multiple Mechanisms to Fine-Tune Viral and Cellular Gene Expression.Modulation of HIV pathogenesis and T-cell signaling by HIV-1 NefInhibition of T-cell receptor-induced actin remodeling and relocalization of Lck are evolutionarily conserved activities of lentiviral Nef proteins.The KT Jeang Retrovirology prize 2016: Frank Kirchhoff.Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease.Molecular Control of HIV and SIV Latency.Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2
P2860
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P2860
Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Inefficient Nef-mediated downm ...... cells in natural SIV infection
@ast
Inefficient Nef-mediated downm ...... cells in natural SIV infection
@en
type
label
Inefficient Nef-mediated downm ...... cells in natural SIV infection
@ast
Inefficient Nef-mediated downm ...... cells in natural SIV infection
@en
prefLabel
Inefficient Nef-mediated downm ...... cells in natural SIV infection
@ast
Inefficient Nef-mediated downm ...... cells in natural SIV infection
@en
P2093
P2860
P1433
P1476
Inefficient Nef-mediated downm ...... cells in natural SIV infection
@en
P2093
Anke Specht
Donald L Sodora
Guido Silvestri
Jan Schmökel
Michael Schindler
Mohammad Khalid
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000107
P577
2008-07-18T00:00:00Z