Structure-activity relationship and metabolic stability studies of backbone cyclization and N-methylation of melanocortin peptides
about
Automated solid-phase peptide synthesis to obtain therapeutic peptidesGetting in shape: controlling peptide bioactivity and bioavailability using conformational constraintsMotif mediated protein-protein interactions as drug targetsApplication of ring-closing metathesis macrocyclization to the development of Tsg101-binding antagonists.Synthesis of chemically modified bioactive peptides: recent advances, challenges and developments for medicinal chemistry.Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic propertiesPeptidic modulators of protein-protein interactions: progress and challenges in computational design.Using peptides to study protein-protein interactions.Macrocycles in new drug discovery.The melanocortin-4 receptor as target for obesity treatment: a systematic review of emerging pharmacological therapeutic options.Strategic approaches to optimizing peptide ADME propertiesReview backbone N-modified peptides: How to meet the challenge of secondary amine acylation.Novel approaches to the design of bioavailable melanotropins.The effect of N-methylation of amino acids (Ac-X-OMe) on solubility and conformation: a DFT study.In vitro evaluation of metal chelators as potential metallo- β -lactamase inhibitors.The effect of N-methylation on transition state mimetic inhibitors of the Plasmodium protease, plasmepsin VA Novel Substance P-Based Hydrogel for Increased Wound Healing Efficiency
P2860
Q27001623-AFDDE8CE-6054-42F1-AE5A-4D82B5BB73A3Q27021652-FDB8B668-54CD-4326-8FDD-47C13C261614Q28079554-6BB1076B-E355-4ED9-B50A-8B9DE050DAD6Q33638005-4DF882B0-E1D8-4A67-BAC1-6C9504C582FEQ33852418-6BF120CF-A26E-4A2C-AAD8-6F6003B79124Q36126184-641C0C58-AF4A-401C-AB12-F6F33C3FC8F2Q36456593-FE54101B-8564-4B9A-8634-14D8CBFB1FC2Q37396099-58C448EA-4899-43DE-AFAF-EEA2B407F765Q37855887-2C6F12D2-6666-4105-BDBF-95754A91B869Q38031632-2EC16A67-4604-4348-A527-3EEF11A096F7Q38115094-0FD3FADB-D668-4FC1-995D-8CE08D84DB44Q38264736-4BAA6E27-B457-4028-8BFD-8C0C885919B9Q38533393-F6BA9D27-498A-4C8A-BCEF-B95C737DE587Q38658728-B993F8F0-DBFA-408C-BC5D-BE19642B28B4Q40626372-2395947D-F616-42AA-A923-50281B18E55EQ40927676-881DEB1F-22C6-4477-B5C6-54FDF4F6C97EQ56983627-6372D3C9-9FF4-4D4B-80D2-D0E581992599Q58696391-DC15D07A-87E2-4FE4-986A-B7D924502B71
P2860
Structure-activity relationship and metabolic stability studies of backbone cyclization and N-methylation of melanocortin peptides
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure-activity relationshi ...... ation of melanocortin peptides
@ast
Structure-activity relationshi ...... ation of melanocortin peptides
@en
type
label
Structure-activity relationshi ...... ation of melanocortin peptides
@ast
Structure-activity relationshi ...... ation of melanocortin peptides
@en
prefLabel
Structure-activity relationshi ...... ation of melanocortin peptides
@ast
Structure-activity relationshi ...... ation of melanocortin peptides
@en
P2093
P2860
P356
P1433
P1476
Structure-activity relationshi ...... ation of melanocortin peptides
@en
P2093
Amnon Hoffman
Carrie Haskell-Luevano
Chaim Gilon
Deborah E Shalev
Eli Safrai
Federico P Portillo
Oded Ovadia
Yaniv Linde
Zhimin Xiang
P2860
P304
P356
10.1002/BIP.21057
P577
2008-01-01T00:00:00Z